DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17829 and hinfp

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001011095.1	Gene:	hinfp / 496508	XenbaseID:	XB-GENE-966256	Length:	443	Species:	Xenopus tropicalis

Alignment Length:	444	Identity:	147/444 - (33%)
Similarity:	226/444 - (50%)	Gaps:	27/444 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KKPAELELTCGWRDC-------QEICTGEWSLNGHIGDHLEHYAKAQDDRGAHAEHTEHQCTWNS 75
            |:...|.|.|.|..|       ::.||       |:.:||..:.....:.....| .|:.|.|..
Frog     7 KRNVSLVLQCEWGSCTHVSSRMEDFCT-------HVSEHLRQHQHEAREEAVDCE-DEYCCHWLG 63

  Fly    76 CDFRTENQVEFERHSYYHGYYLNLLLQGKLECDLHPEIPACTAPARLMEKLPALGQNFRCGWTDC 140
            |.|.|.::.:|.||.|:|.|:..|...|.......|::..|....:....:|.|...|.|.|..|
Frog    64 CGFFTPDRTDFVRHVYFHCYHTKLKQFGLQALQSQPDLNPCQLDTQTRNIIPELQDGFICLWDQC 128

  Fly   141 EREFVSIVEFQDHIVKHAL-FEYDIQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHISTHSNKKQ 204
            |..:.:...:..|:..|.| .||::   ...|....:|.|..|.....::::|.||:.:|:.:|.
Frog   129 ESSYDNAEWYYRHVDTHGLSAEYEV---AGKENRVLLCGWKDCDLSCKSRWKLREHLRSHTQEKV 190

  Fly   205 VACFHCGELFRTKTTLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHVNCYKCTMCDMT 269
            |:|.:||.:|...|..:||||||.....:.|||:.|.|.|||::||:.|:..|||.|||.:||||
Frog   191 VSCPNCGGMFANNTKFYDHLRRQTSLEEHRFQCSHCSKRFATERLLRDHMRNHVNHYKCPLCDMT 255

  Fly   270 CSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSK-TVHQCEHPDCHYSVRTYT 333
            |...|||.:|||:||..::|.||..|:..|....||.:| |..||| ....||:.:|.::.|:.:
Frog   256 CPLPSSLRSHIRFRHSDERPFKCQHCEYSCKNLVDLRRH-QDTHSKMPAFCCEYEECTFTARSMS 319

  Fly   334 QMRRHFLEVH-GNNPILYACHCCERFFKSGKSLSAHLMKKHGFRLPSGHKRFTYRVDENGFYRLE 397
            .::.|..:.| |:....|.||.||:.|..|.:|:.||.|||.|:.||||.||.|:..::||.||:
Frog   320 SIKAHHRKFHEGDCEPRYKCHVCEKCFTRGNNLTVHLRKKHQFKWPSGHPRFRYKEHDDGFLRLQ 384

  Fly   398 TTRLESLEVTQQILSPQVNDSLAKPGTGSCYEIVDPTNTE-----FERIIVSND 446
            ..|.||:|:|:|::..:.........|.:|..:....:.|     ::|.:|..|
Frog   385 LVRYESVELTEQLMKEREKQGAPMDTTTTCLVLSPGGSMESDEGVYDRTVVEKD 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..225	CDD:275368	7/17 (41%)
		C2H2 Zn finger	237..257	CDD:275368	9/19 (47%)
		C2H2 Zn finger	263..284	CDD:275368	12/20 (60%)
		C2H2 Zn finger	292..311	CDD:275368	6/18 (33%)
		C2H2 Zn finger	352..373	CDD:275368	10/20 (50%)
hinfp	NP_001011095.1	C2H2 Zn finger	166..185	CDD:275368	4/18 (22%)
		C2H2 Zn finger	193..215	CDD:275368	11/21 (52%)
		COG5048	<203..384	CDD:227381	80/181 (44%)
		C2H2 Zn finger	223..243	CDD:275368	9/19 (47%)
		C2H2 Zn finger	249..270	CDD:275368	12/20 (60%)
		C2H2 Zn finger	278..298	CDD:275368	7/20 (35%)
		C2H2 Zn finger	339..357	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I6026
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H9174
Inparanoid	1	1.050	284	1.000	Inparanoid score	I2797
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D564393at33208
OrthoFinder	1	1.000	-	-		FOG0005624
OrthoInspector	1	1.000	-	-		oto103379
Panther	1	1.100	-	-	O	PTHR24391
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X96
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160