DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17829 and im:7141269

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_002661922.1	Gene:	im:7141269 / 492560	ZFINID:	ZDB-GENE-041111-134	Length:	368	Species:	Danio rerio

Alignment Length:	371	Identity:	82/371 - (22%)
Similarity:	136/371 - (36%)	Gaps:	81/371 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QSSVPAPQPPGKRKKPAELELTCGWRDCQEICTGEWSLNGHIGDHLEHYAKAQDDRGAHAEHTEH 69
            |:|....:.| ::.||:.|.:.|   .|.:..|.:.||.||:              ..|.....:
Zfish    68 QTSTRTSKSP-QKSKPSSLFICC---QCGKSFTRKQSLEGHM--------------NLHNGEKPY 114

  Fly    70 QCTWNSCDFRTENQVEFERHSYYHGYYLNLLLQGKLECDLHPEIPACTAPARLMEKLPALGQNFR 134
            .|......||.:..:.                       :|..:.....|             :.
Zfish   115 SCQQCGKSFRQKPNLR-----------------------VHMRVHTGEKP-------------YT 143

  Fly   135 CGWTDCEREFVSIVEFQDHIVKHALFEYDIQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHISTH 199
            |  ..|.:.|..:..|:.|:..|.           .|:| .:|.  .|.|..........|...|
Zfish   144 C--KQCGKSFSLVQGFKIHMRSHT-----------GEKP-YVCQ--QCGKGFSQISSFNSHTRIH 192

  Fly   200 SNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRH--VNCYK 262
            :.:|..:|..||:.|..|..|.||:  ...:...:|:|.||.|.|..|:.||.|:..|  ...:.
Zfish   193 TREKPYSCQLCGKDFSIKQHLNDHM--IIHSAEKAFECQQCGKTFFLKRHLKKHIRVHSGEKNFT 255

  Fly   263 CTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHPDCHY 327
            |.:|..:.:...||..|:|. |..:||..|.:|..|..:.:.|..||: .|::....|:  :|..
Zfish   256 CQLCGNSFTQMYSLKRHMRI-HSGEKPYSCQQCGKRFTQNNSLDIHVR-THTERSFTCQ--ECGE 316

  Fly   328 SVRTYTQMRRHFLEVHGNNPILYACHCCERFFKSGKSLSAHLMKKH 373
            |....:.:..| ::.||... .:.|..||:.|....:|:.| |:.|
Zfish   317 SFNLKSDLNNH-VKTHGEEK-AFPCGQCEKSFSRKDNLNRH-MRAH 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	3/16 (19%)
		C2H2 Zn finger	207..225	CDD:275368	8/17 (47%)
		C2H2 Zn finger	237..257	CDD:275368	9/19 (47%)
		C2H2 Zn finger	263..284	CDD:275368	6/20 (30%)
		C2H2 Zn finger	292..311	CDD:275368	6/18 (33%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
im:7141269	XP_002661922.1	COG5048	69..>362	CDD:227381	81/370 (22%)
		C2H2 Zn finger	88..108	CDD:275368	7/36 (19%)
		C2H2 Zn finger	116..136	CDD:275368	4/42 (10%)
		C2H2 Zn finger	144..164	CDD:275368	5/21 (24%)
		C2H2 Zn finger	172..192	CDD:275368	4/21 (19%)
		C2H2 Zn finger	200..220	CDD:275368	8/21 (38%)
		C2H2 Zn finger	228..248	CDD:275368	9/19 (47%)
		C2H2 Zn finger	256..276	CDD:275368	6/20 (30%)
		C2H2 Zn finger	284..304	CDD:275368	6/20 (30%)
		C2H2 Zn finger	311..331	CDD:275368	4/22 (18%)
		C2H2 Zn finger	339..359	CDD:275368	7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910