DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and CG8388

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_611075.1	Gene:	CG8388 / 36763	FlyBaseID:	FBgn0034062	Length:	572	Species:	Drosophila melanogaster

Alignment Length:	374	Identity:	87/374 - (23%)
Similarity:	139/374 - (37%)	Gaps:	85/374 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 KAQDDRGAHAEHTEHQCTWNSCDFRTENQVEF----ERHSYYHGYYL----NLLLQGKLECDLH- 110
            |:|:......||.:.||  :.|:...|:..|.    .|.....||.:    ..|.:|.|...|.
  Fly   218 KSQEFNDYIREHYKVQC--HICNLPMEDFSEMLAHVRREHKQRGYAMCCNRKFLKRGVLVDHLRR 280

  Fly   111 ---PEIPACTAPARL------------MEKLPALGQNFRCGWTDCEREFVSIVEFQDHIVKHALF 160
               ||...|:...|:            |.::.:.|:.:||  ..|.:.|.|.|.::.|.:.|
  Fly   281 HQDPETFKCSICGRVMGHRRSLELHMRMHEIKSRGRLYRC--EQCSKAFYSAVVYERHKLTH--- 340

  Fly   161 EYDIQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHIS-THSNKKQVACFHCGELFRTKTTLFDHL 224
                  .|. |:.|..|  ..|.|...::|.:.:|:. .|.|.....|..||:..|.:..|..|:
  Fly   341 ------IPR-EQWKVPC--THCEKTYPSQYTMQQHVKLVHLNLYAKICDVCGKSIRGREALARHM 396

  Fly   225 RRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHVNCYKCTMCDMTCSSASSLTTHIRYRHLKD-- 287
                |.:|...|.|                      .||.:||...::...|..||:..|..:
  Fly   397 ----EEHTGGPQAA----------------------IKCHLCDSMLTTKYGLARHIKMMHTAENL 435

  Fly   288 KPLKCSECDTRCVRESDLAKHVQIVHSKT-VHQCEHPDCHYSVRTYTQMRRHFLEVHGNNPILYA 351
            :|::|..|...|........|::..|:.. .|||  |.|..:.:...:::.|.....|.  :||.
  Fly   436 QPMQCEFCLKICPSLQAHQHHIKYTHNTARSHQC--PMCEKAFKRPNELKEHMTTHTGE--VLYT 496

  Fly   352 CHCCERFFKSGKSLSAHLMKKHGFRLPSGHKRFTYRVDENGFYRLETTR 400
            |..|.:.|.|..::.||..|.|       .|.:    :||...||..:|
  Fly   497 CPHCPQTFNSNANMHAHRKKVH-------RKEW----EENRHKRLNRSR 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	4/17 (24%)
		C2H2 Zn finger	207..225	CDD:275368	6/17 (35%)
		C2H2 Zn finger	237..257	CDD:275368	1/19 (5%)
		C2H2 Zn finger	263..284	CDD:275368	6/20 (30%)
		C2H2 Zn finger	292..311	CDD:275368	4/18 (22%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
CG8388	NP_611075.1	zf-AD	<21..77	CDD:285071
		C2H2 Zn finger	264..281	CDD:275368	4/16 (25%)
		C2H2 Zn finger	289..309	CDD:275368	2/19 (11%)
		C2H2 Zn finger	320..340	CDD:275368	6/21 (29%)
		C2H2 Zn finger	350..369	CDD:275368	5/20 (25%)
		C2H2 Zn finger	440..461	CDD:275368	4/20 (20%)
		C2H2 Zn finger	469..489	CDD:275368	4/21 (19%)
		C2H2 Zn finger	497..515	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930