DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and Mzf1

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001101940.1	Gene:	Mzf1 / 361508	RGDID:	1308391	Length:	735	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	90/370 - (24%)
Similarity:	137/370 - (37%)	Gaps:	77/370 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 QEICTGE-----------WSLNGHIGDH-LEH-----------------YAKAQDDRGAHAEHTE 68
            |:|.|||           :|.:.|:..| |.|                 .|:.::.|..|.....
  Rat   376 QKIHTGERPFVCGECGRSFSRSSHLLRHQLTHTEERPFVCRDCGQGFVRSARLEEHRRVHTGEQP 440

  Fly    69 HQCTWNSCDFRTENQVEFERHSYYHGYYLNLLLQGKLECDLHPEIPACTAPARLMEKLPALGQNF 133
            .:|......||..:               |||...:    :|.:.|....|.|.:..:|.....|
  Rat   441 FRCAECGQSFRQRS---------------NLLQHQR----IHGDPPGPAPPVRSLAGVPEPPGPF 486

  Fly   134 RCGWTDCEREFVSIVEFQDHIVKHALFEYDIQKTPEDERPKTM-CNWAMCHKHMGNKYRLIEHIS 197
            .|  ::|...|.......:|...|.             ..|:. |  ..|.:..|.:..|::|..
  Rat   487 PC--SECCESFPRRAVLLEHQAVHT-------------GDKSFGC--VECGERFGRRSVLLQHRR 534

  Fly   198 THSNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHV--NC 260
            .||.::..||..||:.||.::.|..|  |:.......|.|.:|.|.|..:..|..|:..|.  ..
  Rat   535 VHSGERPFACAECGQSFRQRSNLTQH--RRIHTGERPFACTECGKAFRQRPTLTQHLRVHTGEKP 597

  Fly   261 YKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHPDC 325
            :.|..|....|....||.|.| .|..:||.:||||.....:.|.|.:|.:|...:....|  |:|
  Rat   598 FACPECGQRFSQRLKLTRHQR-THTGEKPYRCSECGLGFTQVSRLTEHQRIHTGERPFAC--PEC 659

  Fly   326 HYSVRTYTQMRRHFLEVH-GNNPILYACHCCERFFKSGKSLSAHL 369
            ..|.|.:..:.:| ..:| |..|  |||..|.:.|:...:|:.||
  Rat   660 GQSFRQHANLIQH-RRIHTGERP--YACPECGKAFRQRPTLTQHL 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..225	CDD:275368	7/17 (41%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..284	CDD:275368	7/20 (35%)
		C2H2 Zn finger	292..311	CDD:275368	7/18 (39%)
		C2H2 Zn finger	352..373	CDD:275368	6/18 (33%)
Mzf1	NP_001101940.1	SCAN	41..153	CDD:128708
		COG5048	358..717	CDD:227381	90/370 (24%)
		C2H2 Zn finger	359..379	CDD:275368	1/2 (50%)
		C2H2 Zn finger	387..407	CDD:275368	4/19 (21%)
		C2H2 Zn finger	415..435	CDD:275368	2/19 (11%)
		C2H2 Zn finger	443..463	CDD:275370	6/38 (16%)
		C2H2 Zn finger	488..508	CDD:275368	4/21 (19%)
		C2H2 Zn finger	516..536	CDD:275368	5/21 (24%)
		C2H2 Zn finger	544..564	CDD:275368	8/21 (38%)
		C2H2 Zn finger	572..592	CDD:275368	6/19 (32%)
		C2H2 Zn finger	600..620	CDD:275368	7/20 (35%)
		C2H2 Zn finger	628..648	CDD:275368	7/19 (37%)
		C2H2 Zn finger	656..676	CDD:275368	6/22 (27%)
		C2H2 Zn finger	684..704	CDD:275368	6/18 (33%)
		C2H2 Zn finger	712..732	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910