DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17829 and CG9932

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_609599.1	Gene:	CG9932 / 34701	FlyBaseID:	FBgn0262160	Length:	2171	Species:	Drosophila melanogaster

Alignment Length:	486	Identity:	105/486 - (21%)
Similarity:	158/486 - (32%)	Gaps:	155/486 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KRKKPAELE-LTCGWRDCQEI--CTGEWSLNGHIGDHLEHYAKAQDDRGAHAEHTEHQCTWNSCD 77
            |.|..|:.| |.|   .|..:  |..|..::|. ..|.......:|:.|.|.:         ..|
  Fly   601 KLKTGAQHENLVC---QCGHVAKCLSESIIHGK-SCHASAVIIDEDEAGLHED---------DGD 652

  Fly    78 FRTENQVEFERHSYYHGYYLNLLLQGKLECD--LHPEIPACTAPARLMEKLPALGQNFRCGWTDC 140
            .|.|...:.|.|..:..  |||.:.|...|.  .|    .|.:...||..|....:..||
  Fly   653 DRLEIDEDDEDHHSHSA--LNLSVTGSTRCQHCRH----RCKSSTDLMHHLKQCVEAIRC----- 706

  Fly   141 EREFVSIVEFQDHIVKHALFEYDIQKTPE-DERP-------------KTMCNWAMCHKHMGNKYR 191
                             |...||...... |.||             :.:|.|
  Fly   707 -----------------ANEMYDSNSGESGDRRPDSQSLQQQAAVQQQRVCIW------------ 742

  Fly   192 LIEHISTHSNK--KQVACFHCGELFRTKTTLFDHLRRQP------ENNTNSFQCAQCFKFF--AT 246
                     ||  |::.......|.:.|..  .:|.:.|      .|..||:...:....:  .|
  Fly   743 ---------NKATKEIIAAAAASLQQDKNN--HNLVKSPTGSQAASNEENSYYGVETAPGYGEVT 796

  Fly   247 KKLLKSHVVRHVN---CYKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKH 308
            ||:.......:.:   .|||..|....|:||....|| ..||..||.:||.|..|.....|:.||
  Fly   797 KKMTPEEEAANSSLKKVYKCPHCSFWASTASRFHVHI-VGHLNKKPFECSLCSYRSNWRWDITKH 860

  Fly   309 VQIVHSKTVHQCEHPDCHYSVRTYTQMRRHFLEVHGNNPILYACHCCERFFKSGKSLSAHLMKKH 373
            :::   ||:....|......:...|..|                    .:.|..|.::  |||.
  Fly   861 IRL---KTIRDPSHKTAKVLMNDETGRR--------------------NYTKYNKYIT--LMKV- 899

  Fly   374 GFRLPSGHKRFTYRVDENGFYRLETTRLESLEVT-QQILSPQVNDSLAKPGTGSCYEI-VDPTNT 436
                          .:|:|..:|    ::|.|:| .|:.|.......||.|:.|..:| ::|
  Fly   900 --------------TEEDGDPKL----MKSGEMTPNQVASLAFLKDYAKVGSVSGQDITLEP--- 943

  Fly   437 EFERIIVSNDPN---EAQLMGEVVISLPSLA 464
                 ::.|.||   :|.| .:.:|.:|.||
  Fly   944 -----VLPNKPNVLDDAHL-ADNLIRIPLLA 968

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	0/16 (0%)
		C2H2 Zn finger	207..225	CDD:275368	2/17 (12%)
		C2H2 Zn finger	237..257	CDD:275368	3/21 (14%)
		C2H2 Zn finger	263..284	CDD:275368	7/20 (35%)
		C2H2 Zn finger	292..311	CDD:275368	7/18 (39%)
		C2H2 Zn finger	352..373	CDD:275368	5/20 (25%)
CG9932	NP_609599.1	C2H2 Zn finger	339..359	CDD:275368
		C2H2 Zn finger	366..386	CDD:275368
		C2H2 Zn finger	394..414	CDD:275368
		C2H2 Zn finger	816..836	CDD:275370	7/20 (35%)
		C2H2 Zn finger	844..862	CDD:275370	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444654
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930