DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and AgaP_AGAP004269

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_562796.4	Gene:	AgaP_AGAP004269 / 3290990	VectorBaseID:	AGAP004269	Length:	528	Species:	Anopheles gambiae

Alignment Length:	282	Identity:	72/282 - (25%)
Similarity:	113/282 - (40%)	Gaps:	54/282 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 CDLHPEIPACTAPARLMEKLPALGQN-------FRCGWTDCEREFVSIVEFQDHIVKHA-LFEYD 163
            |::      |....|..:|| .:.:|       |:|.:..|.:.|.|.:...:|:.:|. .|||
Mosquito   249 CEI------CFKTFRTRQKL-TVHRNTHLRLAPFKCTFEGCAKAFKSRIGLDEHVARHTNSFEY- 305

  Fly   164 IQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHISTHSNKKQVACFHCGELFRTKTTLFDHLRRQP 228
                        .|:  :|.|...::..|..|...|:.::...|..||:.|:.|..|.||..|
Mosquito   306 ------------TCD--ICSKGFQHRSYLSAHRRAHNTERNFQCGLCGQSFKAKQALLDHKNR-- 354

  Fly   229 ENNTNSFQCAQCFKFFATKKLLKSHVVRH-------VNCYKCTMCDMTCSSASSLTTHIRYRHLK 286
            ......|.|.||.|.:....||:||:.:|       :..|.|:.|....:|.|.|..|:|. |..
Mosquito   355 HLGVKPFACEQCDKQYTKNSLLQSHIQQHHGKRDEAITRYPCSECGKQFTSKSYLNVHMRI-HRN 418

  Fly   287 DKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHPDCHYSVRTYTQMRRHFLEVHGNN----- 346
            ::|..|..|:...:...|||.|:.....:..|.||     :..:.|.  ||:.|:.|..:
Mosquito   419 ERPFVCEVCNKGHITRKDLAVHMLSHTGEKPHTCE-----FCGKAYA--RRNALDWHRRSHTKER 476

  Fly   347 PILYACHCCERFFKSGKSLSAH 368
            |  |.|..|.:.|.....|..|
Mosquito   477 P--YICDICGQTFSQPTPLQVH 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..225	CDD:275368	8/17 (47%)
		C2H2 Zn finger	237..257	CDD:275368	8/19 (42%)
		C2H2 Zn finger	263..284	CDD:275368	7/20 (35%)
		C2H2 Zn finger	292..311	CDD:275368	6/18 (33%)
		C2H2 Zn finger	352..373	CDD:275368	5/17 (29%)
AgaP_AGAP004269	XP_562796.4	zf-AD	<10..62	CDD:214871
		C2H2 Zn finger	249..269	CDD:275368	6/26 (23%)
		C2H2 Zn finger	277..299	CDD:275368	5/21 (24%)
		C2H2 Zn finger	307..327	CDD:275368	5/21 (24%)
		C2H2 Zn finger	335..355	CDD:275368	9/21 (43%)
		C2H2 Zn finger	363..383	CDD:275368	8/19 (42%)
		zf-C2H2	394..416	CDD:278523	8/22 (36%)
		C2H2 Zn finger	396..416	CDD:275368	7/20 (35%)
		zf-H2C2_2	408..429	CDD:290200	7/21 (33%)
		C2H2 Zn finger	424..444	CDD:275368	6/19 (32%)
		zf-H2C2_2	436..461	CDD:290200	8/31 (26%)
		C2H2 Zn finger	452..472	CDD:275368	7/26 (27%)
		zf-H2C2_2	464..489	CDD:290200	7/26 (27%)
		C2H2 Zn finger	480..500	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910