DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and AgaP_AGAP004259

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_562787.4	Gene:	AgaP_AGAP004259 / 3290988	VectorBaseID:	AGAP004259	Length:	493	Species:	Anopheles gambiae

Alignment Length:	443	Identity:	95/443 - (21%)
Similarity:	154/443 - (34%)	Gaps:	110/443 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 EHYAKAQDDRGAHAEHT----EHQCTWNSC-------------DFRTENQVEFER---------- 88
            ||:...||......:.|    |:..|...|             |..:|.::..|:
Mosquito    86 EHFQTTQDSERQSVQETDCSEENPLTEEECQLVIKDHADIYEEDLCSETEILVEQLDVEDGKSII 150

  Fly    89 ------HSYYHGY------------YLNLLLQGKLECDLHPEIPACTAPARLMEKLPALGQNFRC 135
                  .|||..|            .||       ||:......|      ::|::.:..:....
Mosquito   151 EQTADHESYYELYDVVEDVEFGEIEALN-------ECEDDDSQDA------IIERIESTQETNES 202

  Fly   136 GWTDCEREFVSIVEF--------------QDHIVKHALFEYDIQKTPEDERPKTMCNWAMCHKHM 186
            ...|.....|...||              .|.:.:|:...::.::...:.||.. |:  :|:|..
Mosquito   203 SVDDPVESTVQATEFVIECCGCPGVQFPSADELKQHSAQVHENERILTNLRPYE-CD--ICYKRF 264

  Fly   187 GNKYRLIEHISTHSNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNS-------FQCAQCFKFF 244
            .:...|.:|.:....||:..|..||..|.:::.|..|        |||       :.|..|.|.|
Mosquito   265 ISHAALSKHQAAPYRKKKYGCQTCGASFCSRSALHGH--------TNSAHTRDRKYVCDVCQKGF 321

  Fly   245 ATKKLLKSHVVRH-VNCYKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKH 308
            .|...:.||...| ...|:|:.|.......|.|.:| :..|..::|..|.||:.|....|.|..|
Mosquito   322 YTSSTMLSHRQIHGEKKYQCSTCAKKFLRQSDLLSH-QMTHSDERPYGCGECEMRFKCRSHLRDH 385

  Fly   309 VQIVHSKTVHQCEHPD----CHYSVRTYTQMRRHFLEVHGNNPILYACHCCERFFKSGKSLSAHL 369
                  :|||..|...    |.....||...|.|.|.....:|  :.|..|.:.:.....|..|:
Mosquito   386 ------QTVHTGERTKKCRICGKGFGTYGDRRVHELRHENVHP--FKCGYCSKTYGRNYKLQVHI 442

  Fly   370 MKKH----GFRLPSGHKRFTYRVDENGFYRLETTRLESLEVTQQILSPQVNDS 418
            .|:|    .|......:||..|.:..|..|:...::|.:|..:  |..:::|:
Mosquito   443 RKEHTKERPFACSDCPERFFQRWEMLGHQRVVHGKMEGIESVE--LETELHDT 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..225	CDD:275368	6/17 (35%)
		C2H2 Zn finger	237..257	CDD:275368	7/19 (37%)
		C2H2 Zn finger	263..284	CDD:275368	5/20 (25%)
		C2H2 Zn finger	292..311	CDD:275368	7/18 (39%)
		C2H2 Zn finger	352..373	CDD:275368	5/20 (25%)
AgaP_AGAP004259	XP_562787.4	zf-AD	4..76	CDD:214871
		C2H2 Zn finger	221..249	CDD:275368	2/27 (7%)
		C2H2 Zn finger	257..277	CDD:275368	5/21 (24%)
		C2H2 Zn finger	285..306	CDD:275368	9/28 (32%)
		C2H2 Zn finger	314..334	CDD:275368	7/19 (37%)
		C2H2 Zn finger	341..361	CDD:275368	5/20 (25%)
		C2H2 Zn finger	369..389	CDD:275368	8/25 (32%)
		C2H2 Zn finger	397..417	CDD:275368	6/19 (32%)
		C2H2 Zn finger	425..443	CDD:275368	4/17 (24%)
		C2H2 Zn finger	454..473	CDD:275370	4/18 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X96
TreeFam	0	0.000	Not matched by this tool.
	1	1.000