DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17829 and CTCFL

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001255972.1	Gene:	CTCFL / 140690	HGNCID:	16234	Length:	700	Species:	Homo sapiens

Alignment Length:	190	Identity:	62/190 - (32%)
Similarity:	90/190 - (47%)	Gaps:	14/190 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 STHSNKKQVAC---FHCGELFRTKTTLFDHLRRQPENNTNS--FQCAQCFKFFATKKLLKSHVVR 256
            ||.:.:|....   |||.....|.:.: ....|..:.:|:.  ..|..|.|.|.|..||::||..
Human   243 STKNQRKTKGAKGTFHCDVCMFTSSRM-SSFNRHMKTHTSEKPHLCHLCLKTFRTVTLLRNHVNT 306

  Fly   257 HVNC--YKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQ 319
            |...  |||..|:|...::..|..|.||:|..:||.|||.|....|..|.|.:||:....:...|
Human   307 HTGTRPYKCNDCNMAFVTSGELVRHRRYKHTHEKPFKCSMCKYASVEASKLKRHVRSHTGERPFQ 371

  Fly   320 CEHPDCHYSVRTYTQMRRHFLEVHGNNPILYACHCCE-RFFKSGKSLSAHLMKKHGFRLP 378
            |  ..|.|:.|...:::||.....|..|  |.||.|. ||.:|| ::..|:::|||..:|
Human   372 C--CQCSYASRDTYKLKRHMRTHSGEKP--YECHICHTRFTQSG-TMKIHILQKHGENVP 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	1/1 (100%)
		C2H2 Zn finger	207..225	CDD:275368	4/20 (20%)
		C2H2 Zn finger	237..257	CDD:275368	9/19 (47%)
		C2H2 Zn finger	263..284	CDD:275368	7/20 (35%)
		C2H2 Zn finger	292..311	CDD:275368	8/18 (44%)
		C2H2 Zn finger	352..373	CDD:275368	8/21 (38%)
CTCFL	NP_001255972.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	24..55
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..250		2/6 (33%)
		COG5048	<259..403	CDD:227381	47/148 (32%)
		C2H2 Zn finger	259..279	CDD:275368	3/20 (15%)
		zf-H2C2_2	271..296	CDD:290200	6/24 (25%)
		C2H2 Zn finger	287..307	CDD:275368	9/19 (47%)
		zf-H2C2_2	300..324	CDD:290200	9/23 (39%)
		C2H2 Zn finger	315..333	CDD:275368	5/17 (29%)
		C2H2 Zn finger	344..364	CDD:275368	8/19 (42%)
		zf-H2C2_2	357..378	CDD:290200	6/22 (27%)
		C2H2 Zn finger	372..392	CDD:275368	6/21 (29%)
		zf-H2C2_2	385..409	CDD:290200	10/25 (40%)
		C2H2 Zn finger	400..417	CDD:275368	7/17 (41%)
		C2H2 Zn finger	430..448	CDD:275368
		C2H2 Zn finger	460..480	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		zf-H2C2_2	500..525	CDD:290200
		C2H2 Zn finger	516..534	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	569..630
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910