DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and AgaP_AGAP012110

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_320418.4	Gene:	AgaP_AGAP012110 / 1280566	VectorBaseID:	AGAP012110	Length:	512	Species:	Anopheles gambiae

Alignment Length:	452	Identity:	100/452 - (22%)
Similarity:	156/452 - (34%)	Gaps:	143/452 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PQPPGKRKKPAELELTCGWRDCQEICTGEWSLNGHIGDHLEHYAKAQDDRGAHAE-HTE---HQC 71
            ||...::::|           ..:|||    :.|          .|:.|..||.. |..   :||
Mosquito   101 PQHAARKQRP-----------MPKICT----ICG----------VARTDMAAHMRWHNNERPYQC 140

  Fly    72 TWNSCDFRTENQVEFERHSYYHGYYLNLLLQGKL-ECDLHPEIPACTAPARLMEKLPALGQNFRC 135
            .  .|.....|....:.|       :||..:.|| :|||..:..|.|.......::.|..:...|
Mosquito   141 P--HCPKIFLNSSNLKNH-------INLHTREKLYKCDLCDKEFASTTGRSKHREIHATERVHLC 196

  Fly   136 GWTDCEREFVSIVEFQDHIVKHALFEYDIQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHISTHS 200
              |.|.:.|    :::..:.:|.|..:        |.||..|  ::|......|.||.:|...|.
Mosquito   197 --TVCGKRF----KYRASLARHKLIHF--------EEPKQKC--SVCDMMFLTKTRLTKHFMVHM 245

  Fly   201 NKKQVACFHCGELFRTKTTLFDHLR--------------------------RQPENNTNSFQCAQ 239
            |.|..:|..||:.|..|..|..|::                          |:...|..:.||..
Mosquito   246 NVKPFSCEVCGKAFNRKDNLKTHMKTHAAQRKREKKQEPAGIVYLNNLAEHRRMHLNIRTQQCPY 310

  Fly   240 CFKFFATKKLLKSH--VVRHVNCYKCTMCDMTCSS-ASSLTTHIRYRHLKDKPLKCSECDTRCVR 301
            |.|.|..:..|.:|  :..|...|||..|....:| .::|..| |..||..:..:|..|:...|.
Mosquito   311 CEKTFVHRTNLITHLNIHTHDRTYKCEYCGSEFTSYLNNLAEH-RRMHLNIRTQQCPYCEKTFVH 374

  Fly   302 ESDLAKHVQI-VHSKTVHQCEH-------------------------PDCH--YSVRTYTQMRRH 338
            .::|..|:.| .|.:| ::||:                         ..||  ||.:.|  :|.|
Mosquito   375 RTNLITHLNIHTHDRT-YKCEYCGSEFTSVQGLKQHRATHFEGQYACTICHRKYSRKCY--LRVH 436

  Fly   339 FLEVHGN--------------NP-------------ILYACHCCERFFKSGKSLSAHLMKKH 373
            ...||..              ||             .|:.|..|.|.:.:.::|..|:...|
Mosquito   437 HERVHRPKEKHCCLICDRQFLNPTLKEKHMKIHEDGTLHECSLCHRAYNAKRNLLRHIRTAH 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	5/16 (31%)
		C2H2 Zn finger	207..225	CDD:275368	7/17 (41%)
		C2H2 Zn finger	237..257	CDD:275368	6/21 (29%)
		C2H2 Zn finger	263..284	CDD:275368	6/21 (29%)
		C2H2 Zn finger	292..311	CDD:275368	5/18 (28%)
		C2H2 Zn finger	352..373	CDD:275368	5/20 (25%)
AgaP_AGAP012110	XP_320418.4	C2H2 Zn finger	115..132	CDD:275368	7/30 (23%)
		C2H2 Zn finger	140..160	CDD:275368	5/28 (18%)
		C2H2 Zn finger	168..188	CDD:275368	5/19 (26%)
		C2H2 Zn finger	196..216	CDD:275368	6/25 (24%)
		C2H2 Zn finger	224..244	CDD:275368	6/21 (29%)
		zf-C2H2	250..272	CDD:278523	7/21 (33%)
		C2H2 Zn finger	252..272	CDD:275368	7/19 (37%)
		C2H2 Zn finger	308..328	CDD:275368	6/19 (32%)
		C2H2 Zn finger	336..357	CDD:275368	6/21 (29%)
		C2H2 Zn finger	365..385	CDD:275368	5/19 (26%)
		C2H2 Zn finger	393..441	CDD:275368	9/49 (18%)
		C2H2 Zn finger	449..469	CDD:275368	2/19 (11%)
		C2H2 Zn finger	477..496	CDD:275368	5/18 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X96
TreeFam	0	0.000	Not matched by this tool.
	1	1.000