DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and AgaP_AGAP009010

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_319758.4	Gene:	AgaP_AGAP009010 / 1279969	VectorBaseID:	AGAP009010	Length:	433	Species:	Anopheles gambiae

Alignment Length:	286	Identity:	71/286 - (24%)
Similarity:	111/286 - (38%)	Gaps:	69/286 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SVPAPQPPGKRKKPAELELTCGWRDCQEICTGEWSLNGHIGDHLEHYAKAQDDRGAHAEHTEHQC 71
            ||||.||..:|                                   |...   |||......|||
Mosquito   187 SVPAKQPQKRR-----------------------------------YTTT---RGASPNQQVHQC 213

  Fly    72 TWNSCDFRTENQVEFERHSYYHGYYLNLLLQGK--LECDLHPEIPACTAPARL-MEKLPALGQNF 133
            .:....|:..:|:  .||.|.|     |...||  ..|::..::...::..|. |..:....:.:
Mosquito   214 KYCRKTFKCNSQL--TRHEYIH-----LTQDGKPGYSCEICRKVFTKSSIRRAHMRMMHEGAKPY 271

  Fly   134 RCGWTDCEREFVSIVEFQDHIVKHALFEYDIQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHIST 198
            .|  .:|.:.|.|....::|.:.|:           :||| ..|  |.|.|...|..||..|..|
Mosquito   272 MC--EECGKPFSSKGALKEHYIVHS-----------EERP-FKC--AYCPKSFKNAPRLKTHEDT 320

  Fly   199 HSNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHVNC--Y 261
            |::...| |.|||....||.||..|:  ...::...|:|.:|...:...|.||:|::.|...  |
Mosquito   321 HNDTLYV-CPHCGLKLNTKRTLNMHM--VVHSDQKKFKCQECGNEYKRSKALKAHLILHTGLRPY 382

  Fly   262 KCTMCDMTCSSASSLTTHIRYRHLKD 287
            :|..||.|.::.|:..:|.:..|.::
Mosquito   383 QCPFCDKTFANGSNCRSHKKKFHPRE 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	6/16 (38%)
		C2H2 Zn finger	207..225	CDD:275368	9/17 (53%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..284	CDD:275368	6/20 (30%)
		C2H2 Zn finger	292..311	CDD:275368
		C2H2 Zn finger	352..373	CDD:275368
AgaP_AGAP009010	XP_319758.4	ASF1_hist_chap	<72..192	CDD:304562	4/4 (100%)
		COG5048	<171..402	CDD:227381	70/278 (25%)
		C2H2 Zn finger	213..233	CDD:275368	6/21 (29%)
		C2H2 Zn finger	244..265	CDD:275368	3/20 (15%)
		C2H2 Zn finger	273..293	CDD:275368	5/21 (24%)
		zf-H2C2_2	285..310	CDD:290200	9/38 (24%)
		C2H2 Zn finger	301..321	CDD:275368	8/21 (38%)
		C2H2 Zn finger	328..348	CDD:275368	9/21 (43%)
		C2H2 Zn finger	356..376	CDD:275368	6/19 (32%)
		zf-H2C2_2	368..393	CDD:290200	9/24 (38%)
		C2H2 Zn finger	384..402	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910