DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and AgaP_AGAP002920

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_311985.4	Gene:	AgaP_AGAP002920 / 1273044	VectorBaseID:	AGAP002920	Length:	667	Species:	Anopheles gambiae

Alignment Length:	424	Identity:	126/424 - (29%)
Similarity:	197/424 - (46%)	Gaps:	33/424 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 CGWRDCQEICTGEWSLNGHIGDHLEHYAKAQDDRGAHAEHTEHQCTWNSCDFRTENQVEFERHSY 91
            |.|..|:.:...:.....|:..|.|        .....|..::.|.|:.|::.||:..||..|.:
Mosquito   123 CEWGKCKFMSGTDRKYFLHVESHAE--------LALETEAGKYTCRWDLCEYSTEDGYEFVGHVH 179

  Fly    92 YHGYYLNLLLQGKLECDLH--PEIPACTAPARLMEKLPALGQNFRCGWTDCEREFVSIVEFQDHI 154
            ||.|:..|.:.|   ..||  .::|.|...:|....:......|:|.|.:|...|...:.|..|:
Mosquito   180 YHAYHTKLKVHG---ASLHLLLKLPNCNNDSRTRNTITNRPVTFQCEWNECSDRFNKALHFFHHV 241

  Fly   155 VKHALFEYDIQKTPEDERPKTMCNWAMC--HKHMGNKYRLIEHISTHSNKKQVACFHCGELFRTK 217
            ..|.   .|:....:....|..|.||:|  ...:.::..|::|:.:|:.::.:|||:||..||.:
Mosquito   242 KGHI---DDMWPAGKWSSQKFSCKWALCTTKSKLTSRKDLMKHLVSHTTERLIACFNCGTHFRIR 303

  Fly   218 TTLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHVNCYKCTMCDMTCSSASSLTTHIRY 282
            ....||..||.|.....:||.||.:::|||.||.:|:..|...:.|.:|....||...|..|||.
Mosquito   304 DKFVDHCNRQLEIAHRKYQCDQCGRYYATKPLLNNHMQYHRQAHACELCPAKFSSPGLLAAHIRI 368

  Fly   283 RHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHPDCHYSVRTYTQMRRHFLEVHGNNP 347
            :||..:..||.:||.....:.||..|: :.|...:.:||...|:...||...:::| :..|.|.|
Mosquito   369 KHLNQRDFKCPQCDYASHYKKDLVAHI-LGHEGKLFRCEEFGCNVVYRTLLGLKKH-ISWHYNLP 431

  Fly   348 I-LYACHCCERF--FKSGKSLSAHLMKKHGFRLPSGHKRFTYRVDENGFYRLET---TRLESLEV 406
            . :||||.|:..  :||..||..|.:.||....|.|..||.::.|.:|.|||::   .:|.....
Mosquito   432 TPVYACHLCDNHLRYKSSTSLKKHFLFKHDMARPPGMSRFRFKPDTDGMYRLQSFVDEKLRKHHE 496

  Fly   407 TQQILSPQVNDSLAKPGTGSCYEIVDPTNTEFER 440
            .||.|..|.|...|..|||       ||.::.:|
Mosquito   497 EQQPLEQQQNSGEANEGTG-------PTGSKGKR 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	3/18 (17%)
		C2H2 Zn finger	207..225	CDD:275368	8/17 (47%)
		C2H2 Zn finger	237..257	CDD:275368	9/19 (47%)
		C2H2 Zn finger	263..284	CDD:275368	8/20 (40%)
		C2H2 Zn finger	292..311	CDD:275368	6/18 (33%)
		C2H2 Zn finger	352..373	CDD:275368	8/22 (36%)
AgaP_AGAP002920	XP_311985.4	C2H2 Zn finger	293..318	CDD:275368	11/24 (46%)
		C2H2 Zn finger	323..343	CDD:275368	9/19 (47%)
		C2H2 Zn finger	349..370	CDD:275368	8/20 (40%)
		C2H2 Zn finger	378..398	CDD:275368	6/20 (30%)
		zf-C2H2_8	379..456	CDD:292531	24/78 (31%)
		C2H2 Zn finger	405..427	CDD:275368	6/22 (27%)
		C2H2 Zn finger	437..455	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	96	1.000	Domainoid score	I13756
eggNOG	1	0.900	-	-		E1_KOG3608
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	214	1.000	Inparanoid score	I6040
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D564393at33208
OrthoFinder	1	1.000	-	-		FOG0005624
OrthoInspector	1	1.000	-	-		oto107803
Panther	1	1.100	-	-	LDO	PTHR24391
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X96
TreeFam	1	0.960	-	-
	11	10.930