DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and AgaP_AGAP011181

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_309466.4	Gene:	AgaP_AGAP011181 / 1270746	VectorBaseID:	AGAP011181	Length:	346	Species:	Anopheles gambiae

Alignment Length:	342	Identity:	76/342 - (22%)
Similarity:	113/342 - (33%)	Gaps:	99/342 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 CQEICTGEWSLNGHIGDHLEHYAKAQDDRGAHAEHTEHQCTWNSCDFRTENQVEFERHSYYHGYY 96
            |:|:....|....| .|..|...:.||.....::..:.|.        .|::|:
Mosquito    68 CREVDQKLWHRRQH-SDKTEGAVQEQDPANTLSQSNDEQA--------PESKVQ----------- 112

  Fly    97 LNLLLQGKLECDLHPEIPACTAPARLMEKLPALGQNFRCGWTDCEREFVSIVEFQDHIVKHALFE 161
                         |..:           |......|..|.......||. :||..|   .|..:|
Mosquito   113 -------------HMHV-----------KSDEASPNPPCDGKSTNEEFY-VVELTD---AHHEYE 149

  Fly   162 YDIQKTPEDER----PKTMCNWAMCHKHMGNKYRLIEHISTHSNKKQVACFHCGELFRTKTTLFD 222
            .|:   |..|.    |.|..:.|..:           |:..|:.:|:..|..|...|..|..|..
Mosquito   150 LDL---PGSESIPVPPATTTSNATDN-----------HMLVHTGEKRYVCPVCQRAFAQKGNLTY 200

  Fly   223 HLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHVNCYKCTMCDMTCSSASSLTTHIRYRHLKD 287
            ||      |.::..|.                      |:|..||.......||..|:|| |.:.
Mosquito   201 HL------NQHTGHCP----------------------YRCDQCDKAFKDPHSLVVHMRY-HTQS 236

  Fly   288 KPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHPDCHYSVRTYTQMRRHFLEVHGNNPILYAC 352
            ||..||||::..|..|.|.||::....:..:||  .:|..|.::...:|.|.|. | .....:.|
Mosquito   237 KPFACSECESSFVNSSGLKKHLRTHTGERPYQC--GECKKSFKSSHNLRLHKLS-H-TKERRFQC 297

  Fly   353 HCCERFFKSGKSLSAHL 369
            ..|||:|.....|..|:
Mosquito   298 DLCERWFSYKNVLQTHM 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	1/16 (6%)
		C2H2 Zn finger	207..225	CDD:275368	6/17 (35%)
		C2H2 Zn finger	237..257	CDD:275368	1/19 (5%)
		C2H2 Zn finger	263..284	CDD:275368	8/20 (40%)
		C2H2 Zn finger	292..311	CDD:275368	9/18 (50%)
		C2H2 Zn finger	352..373	CDD:275368	7/18 (39%)
AgaP_AGAP011181	XP_309466.4	C2H2 Zn finger	213..233	CDD:275368	8/20 (40%)
		zf-H2C2_2	225..250	CDD:290200	12/25 (48%)
		C2H2 Zn finger	241..261	CDD:275368	9/19 (47%)
		zf-H2C2_2	254..278	CDD:290200	7/25 (28%)
		C2H2 Zn finger	269..289	CDD:275368	6/22 (27%)
		C2H2 Zn finger	297..317	CDD:275368	7/18 (39%)
		zf-AD	5..75	CDD:285071	2/6 (33%)
		COG5048	<116..302	CDD:227381	59/247 (24%)
		zf-H2C2_2	172..194	CDD:290200	6/32 (19%)
		C2H2 Zn finger	185..205	CDD:275368	8/25 (32%)
		zf-C2H2	211..233	CDD:278523	9/22 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X96
TreeFam	0	0.000	Not matched by this tool.
	1	1.000