DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and AgaP_AGAP007514

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_308362.4	Gene:	AgaP_AGAP007514 / 1269713	VectorBaseID:	AGAP007514	Length:	525	Species:	Anopheles gambiae

Alignment Length:	403	Identity:	88/403 - (21%)
Similarity:	137/403 - (33%)	Gaps:	96/403 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RPQSSVPAPQPPGKRKKPAELELTCGWRDCQEICTGEWSLNGHIGDHLEHYAKAQDDRGAHAEHT 67
            |..||.|..:.|.:.:.|...:.:.......::.                 |:.::|...|..:.
Mosquito   164 RSDSSSPDRRKPKRERNPKRPQTSDNETKQSKVA-----------------AQKEEDESLHNFYK 211

  Fly    68 EHQCTWNSCDFRT----ENQVEFERHSYYHGYYLNLLLQGKLECDLHPEI----PACTAPARLME 124
            ...|  ..||.:.    |.|::|       |.:..||...| |...|.::    |.|....|..:
Mosquito   212 RIVC--EVCDIQRMLVGEPQIDF-------GTWRALLRHTK-EVHKHDKVYVKCPVCEMKMRTKQ 266

  Fly   125 KL---------PALGQNFRCGWTDCEREFVSIVEFQDHIVKHALFEYDIQKTPEDERPKTMCNWA 180
            .|         |   :.:||..  |..             ||...:..||...::.  :..|:
Mosquito   267 TLLQHMDWHENP---EKYRCEL--CGE-------------KHQNMKEHIQNKHQER--QFCCD-- 309

  Fly   181 MCHKHMGNKYRLIEHISTHSNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNSFQCAQCFKFFA 245
            :|.|....|.||..|:.....:|.:.|..|.:.| ||.|:.||.|   ..::..|.|..|.|.|.
Mosquito   310 VCGKKFPFKKRLTVHMKKMHVEKDIICDQCQKPF-TKYTIEDHKR---SVHSARFVCEHCPKTFN 370

  Fly   246 TKKLLKSHVVRHVNCYK------CTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDT--RCVRE 302
            ::..|..|:..|....:      ||:|.........||.||:..|.....:.|..|..  :|.|
Mosquito   371 SRFRLLQHMEEHDESLRNSTSVPCTICGQVMRDKYILTRHIKLMHTVQPAVSCETCGKTFKCKR- 434

  Fly   303 SDLAKHVQIVHSKTVHQCEHPD-------CHYSVRTYTQMRRHFLEVHGNNPILYACHCCERFFK 360
             :|:.|:..|       |..|.       |....|...:::.| :..|...| ||.|..|...|:
Mosquito   435 -NLSVHMTNV-------CMEPTRLYPCTICGKEFRRKNKLKEH-MSTHTGKP-LYMCSFCPETFR 489

  Fly   361 SGKSLSAHLMKKH 373
            ....|..|....|
Mosquito   490 QDTHLYHHRKNAH 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	6/16 (38%)
		C2H2 Zn finger	207..225	CDD:275368	8/17 (47%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..284	CDD:275368	7/20 (35%)
		C2H2 Zn finger	292..311	CDD:275368	6/20 (30%)
		C2H2 Zn finger	352..373	CDD:275368	5/20 (25%)
AgaP_AGAP007514	XP_308362.4	zf-AD	6..74	CDD:214871
		C2H2 Zn finger	255..275	CDD:275368	4/19 (21%)
		C2H2 Zn finger	283..300	CDD:275368	6/31 (19%)
		C2H2 Zn finger	308..328	CDD:275368	7/21 (33%)
		C2H2 Zn finger	336..356	CDD:275368	9/23 (39%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	394..415	CDD:275368	7/20 (35%)
		C2H2 Zn finger	423..445	CDD:275368	7/30 (23%)
		C2H2 Zn finger	453..473	CDD:275368	3/20 (15%)
		C2H2 Zn finger	481..499	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910