DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17829 and LOC110439525

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_021331300.1	Gene:	LOC110439525 / 110439525	-ID:	-	Length:	434	Species:	Danio rerio

Alignment Length:	397	Identity:	97/397 - (24%)
Similarity:	152/397 - (38%)	Gaps:	101/397 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RKKPAELELTC-----------GWRDCQEICTGE-----------WSLNGHIGDHLEHYAKAQDD 59
            |:||    .||           |:.:...|.|||           ::...::..|:..:.|.:
Zfish    97 REKP----YTCEQCGKSFGHIQGFENHMRIHTGEKPFSCKQCGKSFTQKANLDVHMRVHTKER-- 155

  Fly    60 RGAHAEHTEHQC----TWNSCDFRTENQVEF-ER--------HSYYH-GYYLNLLLQGKLECDLH 110
                 .:|..||    |:.. .|.|..::.. ||        .|:|| |.:.           :|
Zfish   156 -----PYTCEQCGKSFTYKQ-GFTTHMRIHTGERPYTCQQCKKSFYHPGNFA-----------VH 203

  Fly   111 PEIPACTAPARLMEKLPALGQNFRCGWTDCEREFVSIVEFQDHIVKHALFEYDIQKTPEDERPKT 175
            ..|.....|             :.|  ..|.:.|.....|..|:..|.           .|||.:
Zfish   204 MRIHTGERP-------------YTC--QQCGKSFYQSGNFAAHMRIHT-----------GERPYS 242

  Fly   176 MCNWAMCHKHMGNKYRLIEHISTHSNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNSFQCAQC 240
             |  ..|.|.......|..|:.||:..:...|.|||:.|..|..|..|:|.......::  |.||
Zfish   243 -C--IQCGKSFKQNCTLEVHMRTHTGDRSFICTHCGKHFSQKHDLNIHMRIHTGEKPHT--CTQC 302

  Fly   241 FKFFATKKLLKSHVVRHV--NCYKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRES 303
            .|.|..|.:..:|:..|.  ..|:||.|..|....|:|..|:: .|..:||..|::|..|...::
Zfish   303 GKRFTQKTIRDNHMRIHTGEKPYRCTECGKTFPHKSTLKHHMK-THTGEKPFTCAQCGKRFTTKA 366

  Fly   304 DLAKHVQIVHSKT-VHQCEHPDCHYSVRTYTQMRRHFLEVH-GNNPILYACHCCERFFKSGKSLS 366
            .| |::...|:.| |..|:  .|..|:.....:|:|..::: |.:|  :.|..|.:.|||.:||:
Zfish   367 SL-KNLMDNHTGTIVLTCD--QCEKSLTRKDSIRKHIRKINSGEDP--FRCSECGKGFKSKRSLN 426

  Fly   367 AHLMKKH 373
            .|| |.|
Zfish   427 THL-KLH 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..225	CDD:275368	8/17 (47%)
		C2H2 Zn finger	237..257	CDD:275368	7/19 (37%)
		C2H2 Zn finger	263..284	CDD:275368	7/20 (35%)
		C2H2 Zn finger	292..311	CDD:275368	5/18 (28%)
		C2H2 Zn finger	352..373	CDD:275368	10/20 (50%)
LOC110439525	XP_021331300.1	COG5048	<70..360	CDD:227381	73/317 (23%)
		C2H2 Zn finger	103..123	CDD:275368	2/19 (11%)
		C2H2 Zn finger	131..151	CDD:275368	1/19 (5%)
		C2H2 Zn finger	159..179	CDD:275368	5/20 (25%)
		C2H2 Zn finger	187..207	CDD:275368	5/30 (17%)
		C2H2 Zn finger	215..235	CDD:275368	5/21 (24%)
		C2H2 Zn finger	243..263	CDD:275368	5/21 (24%)
		C2H2 Zn finger	271..291	CDD:275368	9/19 (47%)
		C2H2 Zn finger	299..319	CDD:275368	7/19 (37%)
		C2H2 Zn finger	327..347	CDD:275368	7/20 (35%)
		C2H2 Zn finger	412..432	CDD:275368	10/20 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910