DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and LOC100486443

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_031759800.1	Gene:	LOC100486443 / 100486443	-ID:	-	Length:	1764	Species:	Xenopus tropicalis

Alignment Length:	460	Identity:	104/460 - (22%)
Similarity:	141/460 - (30%)	Gaps:	142/460 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 CDFRTENQVEFERH-----------------SYYHGYYLNLLLQGKLECDLHPEIPACTAPARLM 123
            |...|.|:..:.||                 ||.....|.|.:|      :|......|.|
Frog  1121 CGRVTPNKSNYLRHLRTHTGEKPYTCPECGRSYIQSSQLALHIQ------IHMGEKPYTCP---- 1175

  Fly   124 EKLPALGQNFRCGWT-----------------------DCEREFVSIVEFQDHIVKHA------- 158
                      .||.|                       :|.:.|....:...|...|.
Frog  1176 ----------ECGKTFSHSSQLCTHRKSHTGEKPYTCPECGKTFSHSSQLCTHRKSHTGEKPYTC 1230

  Fly   159 -----LFEYDIQ-----KTPEDERPKTMCNWAMCHKHMGNKYRLIEHISTHSNKKQVACFHCGEL 213
                 .|.:..|     |:...|:|.| |  ..|.|...:..:|..|..:|:.:|...|..||:.
Frog  1231 PECGKTFSHSSQLCTHRKSHTGEKPYT-C--PECGKTFSHSSQLCTHRKSHTGEKPYTCPECGKT 1292

  Fly   214 FRTKTTLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHV--NCYKCTMCDMTCSSASSL 276
            |...:.|..|  |:.......:.|.:|.|.|:....|.:|...|.  ..|.|..|..|.|.:|.|
Frog  1293 FSHSSQLCTH--RKSHTGEKPYTCPECGKTFSRSSQLCTHRKSHTGEKPYTCPECGKTFSRSSQL 1355

  Fly   277 TTHIRYRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHP----DCHYSVRTYTQMRR 337
            .|| |..|..:||..|.||.....|.|.|..|      :..|..|.|    :|......|:|...
Frog  1356 CTH-RKSHTGEKPYTCPECGKTFSRSSQLCTH------RKSHTGEKPFSCRECGKRFGRYSQALI 1413

  Fly   338 HFLEVHGNNPILYACHCCERFFKSGKSLSAHLMKKHG---FRLPSGHKRFTYRVDENGFYRLETT 399
            |.....|..|  |||..|.:.|...|.|:.|.|...|   |..|...|.|              .
Frog  1414 HLRSHTGEKP--YACPQCAKAFGDKKHLTRHQMSHSGERPFPCPRCGKSF--------------R 1462

  Fly   400 RLESLEVTQQILSPQVNDSLAKPGTGSCYEIVDPTNTEFER--------------IIVSNDPNEA 450
            |.|.|...|::..|.            |:  ::||....:|              .:|.|:....
Frog  1463 RKEHLSRHQKMRGPH------------CF--LNPTKGRQKREWTWHLHAKPKAPGPVVGNEVAPL 1513

  Fly   451 QLMGE 455
            .|.||
Frog  1514 YLGGE 1518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..225	CDD:275368	6/17 (35%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..284	CDD:275368	9/20 (45%)
		C2H2 Zn finger	292..311	CDD:275368	7/18 (39%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
LOC100486443	XP_031759800.1	KRAB	8..47	CDD:396083
		eNOPS_SF	291..>324	CDD:414955
		C2H2 Zn finger	663..683	CDD:275368
		COG5048	687..>987	CDD:227381
		C2H2 Zn finger	691..711	CDD:275368
		C2H2 Zn finger	719..739	CDD:275368
		C2H2 Zn finger	747..767	CDD:275368
		C2H2 Zn finger	775..795	CDD:275368
		C2H2 Zn finger	803..823	CDD:275368
		C2H2 Zn finger	915..935	CDD:275368
		COG5048	938..1386	CDD:227381	66/290 (23%)
		C2H2 Zn finger	943..963	CDD:275368
		C2H2 Zn finger	971..988	CDD:275368
		C2H2 Zn finger	1118..1138	CDD:275368	5/16 (31%)
		C2H2 Zn finger	1146..1166	CDD:275368	5/25 (20%)
		C2H2 Zn finger	1174..1194	CDD:275368	4/33 (12%)
		C2H2 Zn finger	1202..1222	CDD:275368	3/19 (16%)
		C2H2 Zn finger	1230..1250	CDD:275368	3/19 (16%)
		C2H2 Zn finger	1258..1278	CDD:275368	5/21 (24%)
		C2H2 Zn finger	1286..1306	CDD:275368	7/21 (33%)
		COG5048	1292..1723	CDD:227381	68/266 (26%)
		C2H2 Zn finger	1314..1334	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1342..1362	CDD:275368	9/20 (45%)
		C2H2 Zn finger	1370..1390	CDD:275368	7/25 (28%)
		C2H2 Zn finger	1398..1418	CDD:275368	4/19 (21%)
		C2H2 Zn finger	1426..1446	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1454..1472	CDD:275368	6/31 (19%)
		C2H2 Zn finger	1567..1587	CDD:275368
		C2H2 Zn finger	1595..1615	CDD:275368
		C2H2 Zn finger	1623..1643	CDD:275368
		C2H2 Zn finger	1651..1671	CDD:275368
		C2H2 Zn finger	1679..1699	CDD:275368
		C2H2 Zn finger	1707..1727	CDD:275368
		zf-H2C2_2	1720..1744	CDD:404364
		C2H2 Zn finger	1735..1754	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910