DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and Ctcfl

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001309415.1	Gene:	Ctcfl / 100360757	RGDID:	2321501	Length:	645	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	85/365 - (23%)
Similarity:	132/365 - (36%)	Gaps:	97/365 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 AKAQDDRGAHAEHTEHQCTWNSCDFRTENQVEFERHSYYHG----YYLNLLLQGKLECDL---HP 111
            ||.:..|.........||  ::|.|.:.....|.||...|.    :..:|.|:......|   |.
  Rat   240 AKPKPQRQTKGRPRTFQC--DTCPFTSSKLSTFNRHIKIHSDERPHLCHLCLKSFRTVTLLRNHV 302

  Fly   112 EIPACTAPARLMEKLPALGQNFRCGWTDCEREFVSIVEFQDHIVKHALFEYDIQKTPEDERPKTM 176
            .....|.|             ::||  ||:..||:..|    :|:|..:::    |.|.....::
  Rat   303 NTHTGTRP-------------YKCG--DCDMAFVTSGE----LVRHRRYKH----THEKPFKCSL 344

  Fly   177 CNWAM---------CHKHMGNK--------------YRLIEHISTHSNKKQVACFHCGELFRTKT 218
            |.:|.         ...|.|.:              |:|..|:.|||.:|...|..|...|....
  Rat   345 CKYASVEASKLKRHIRSHTGERPFQCSQCAYASKDTYKLKRHMRTHSGEKPYECPTCHARFTQSG 409

  Fly   219 TLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRHVNCY-----KCTMCDMTCSSASSLTT 278
            |:..|:.::...|....:|..|....|.|..|:.| :|:::.:     ||..|........:|..
  Rat   410 TMKIHIAQKHGENVPKHECPHCATIIARKSDLRVH-LRNLHGHSPEEIKCRYCPAAFHERYALLQ 473

  Fly   279 HIRYRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHPDCHYSVRTYTQMRRHFLEVH 343
            |.| .|..:|..||.:||..|.:|..|..|                    :||:|
  Rat   474 HQR-THKNEKKFKCKQCDYACKQERCLTAH--------------------MRTHT---------- 507

  Fly   344 GNNPILYACHCCERFFKSGKSLSAHLMKKH--GFRLPSGH 381
            |..|  ::|..|.:.|:..:.|:.||.|.|  .| :||.|
  Rat   508 GERP--FSCLTCNKHFRQKQLLTVHLRKYHDPSF-VPSVH 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	5/30 (17%)
		C2H2 Zn finger	207..225	CDD:275368	5/17 (29%)
		C2H2 Zn finger	237..257	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..284	CDD:275368	5/20 (25%)
		C2H2 Zn finger	292..311	CDD:275368	7/18 (39%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
Ctcfl	NP_001309415.1	C2H2 Zn finger	257..277	CDD:275368	6/21 (29%)
		C2H2 Zn finger	285..305	CDD:275368	4/19 (21%)
		zf-H2C2_2	298..322	CDD:290200	8/38 (21%)
		C2H2 Zn finger	313..334	CDD:275368	9/26 (35%)
		COG5048	336..>398	CDD:227381	12/61 (20%)
		C2H2 Zn finger	342..362	CDD:275368	2/19 (11%)
		zf-H2C2_2	355..378	CDD:290200	2/22 (9%)
		C2H2 Zn finger	370..390	CDD:275368	3/19 (16%)
		zf-H2C2_2	383..407	CDD:290200	9/23 (39%)
		C2H2 Zn finger	398..415	CDD:275370	4/16 (25%)
		C2H2 Zn finger	428..451	CDD:275368	7/23 (30%)
		C2H2 Zn finger	458..478	CDD:275368	5/20 (25%)
		zf-H2C2_2	470..495	CDD:290200	10/25 (40%)
		C2H2 Zn finger	486..506	CDD:275368	8/39 (21%)
		zf-H2C2_2	499..523	CDD:290200	10/55 (18%)
		C2H2 Zn finger	514..532	CDD:275368	5/17 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910