DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and znf1079

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_005159263.2	Gene:	znf1079 / 100333893	ZFINID:	ZDB-GENE-110913-68	Length:	332	Species:	Danio rerio

Alignment Length:	361	Identity:	90/361 - (24%)
Similarity:	139/361 - (38%)	Gaps:	93/361 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 EHTEHQCTWNSCDFRTENQVEFERH---------------SYYHGYYLNLLLQGKLECD------ 108
            |.|.|   ||    :||.: :||:|               |...|.:     :.|..|:
Zfish     5 EETHH---WN----KTEEK-QFEKHQETTTDEKPTLTEKTSSCGGPW-----KSKSACNFTCLQC 56

  Fly   109 -----------LHPEIPACTAPARLMEKLPALGQNF----------------RCGWT--DCEREF 144
                       :|..:.....|    ...|..|::|                || :|  .|.:.|
Zfish    57 GNCFTRKHNLQVHMRVHTGEKP----YSCPQCGKSFKQNGYLKVHMRTHTGERC-YTCQQCGQRF 116

  Fly   145 VSIVEFQDHIVKHALFEYDIQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHISTHSNKKQVACFH 209
            .:...|..|:..|.           .|||.| |  ..|.|.:.....|..|:..|:.:|..:|..
Zfish   117 YTTGNFAQHMRIHT-----------GERPYT-C--LQCGKSLYQSANLAAHMRIHTVEKPYSCIQ 167

  Fly   210 CGELFRTKTTLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRH--VNCYKCTMCDMTCSS 272
            ||:.|:..:||..|:|  ..|:...|.|.||.|.||.|:.|:.|:..|  ...|.||.|..:...
Zfish   168 CGKSFKQNSTLEAHIR--AHNDGRIFSCQQCGKSFAQKQDLEIHMRIHSGKKPYTCTECGKSFRF 230

  Fly   273 ASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHPDCHYSVRTYTQMRR 337
            .|:|..|: ..|.::||..|::|......:|.|..|:.:.....|..|:  .|..|:.....::.
Zfish   231 KSTLKQHM-ISHTREKPFTCAQCGRSFTTKSSLMNHMNVHTGTIVFTCD--QCGKSLTRKDSIKN 292

  Fly   338 HFLEVHGNNPILYACHCCERFFKSGKSLSAHLMKKH 373
            | ::.|...  .::|..|.:.|||.:||:.| ||.|
Zfish   293 H-MKTHSVE--RFSCCECGKSFKSERSLNTH-MKLH 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..225	CDD:275368	7/17 (41%)
		C2H2 Zn finger	237..257	CDD:275368	9/19 (47%)
		C2H2 Zn finger	263..284	CDD:275368	6/20 (30%)
		C2H2 Zn finger	292..311	CDD:275368	5/18 (28%)
		C2H2 Zn finger	352..373	CDD:275368	10/20 (50%)
znf1079	XP_005159263.2	C2H2 Zn finger	53..73	CDD:275368	1/19 (5%)
		zf-H2C2_2	65..90	CDD:290200	5/28 (18%)
		C2H2 Zn finger	81..101	CDD:275368	3/19 (16%)
		C2H2 Zn finger	109..129	CDD:275368	4/19 (21%)
		C2H2 Zn finger	137..157	CDD:275368	5/21 (24%)
		zf-H2C2_2	149..174	CDD:290200	8/24 (33%)
		COG5048	<161..320	CDD:227381	49/166 (30%)
		C2H2 Zn finger	165..185	CDD:275368	8/21 (38%)
		C2H2 Zn finger	193..213	CDD:275368	9/19 (47%)
		zf-H2C2_2	205..228	CDD:290200	7/22 (32%)
		C2H2 Zn finger	221..241	CDD:275368	6/20 (30%)
		zf-H2C2_2	234..258	CDD:290200	7/24 (29%)
		C2H2 Zn finger	249..269	CDD:275368	5/19 (26%)
		zf-C2H2_2	252..>322	CDD:289522	18/75 (24%)
		C2H2 Zn finger	277..297	CDD:275368	4/22 (18%)
		C2H2 Zn finger	304..324	CDD:275368	10/20 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910