DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and zfx

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_002935227.1	Gene:	zfx / 100038167	XenbaseID:	XB-GENE-479751	Length:	793	Species:	Xenopus tropicalis

Alignment Length:	380	Identity:	98/380 - (25%)
Similarity:	152/380 - (40%)	Gaps:	60/380 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 ICTGEWSLNG----HIGDHLEHYAKAQDDRGAHAEHTEHQCTWNSCDFRTENQVEFERHSYYHGY 95
            ||..::...|    |:.:|.||.|:           .:::||  .||:.|..:|....|...|..
Frog   414 ICGKKFKSRGFLKRHMKNHPEHLAR-----------KKYRCT--DCDYTTNKKVSLHNHLESHKL 465

  Fly    96 YLNLLLQGK-LECD------LHPEIPACTAPARLMEKLPALGQNFRCGWTDCEREFVSIVEFQDH 153
            ...::...| |||:      ||..   .....:|..|..|..:..||.:.|.|..       :..
Frog   466 TAAVIKTEKDLECEECGKIFLHAN---ALFAHKLTHKEKAGNKMHRCKFCDYETA-------EQG 520

  Fly   154 IVKHALFEYDIQKTPEDERPKTMCNWAMCHKHMGNKYRLIEHISTHSNKKQVACFHCGELFRTKT 218
            ::...|.....:..|.      :|  ..|.|...:...|.:|:.||:.:|...|.:|.......:
Frog   521 LLNRHLLAVHSKSFPH------IC--VECGKGFRHPSELKKHMRTHTGEKPYLCQYCDYRSADSS 577

  Fly   219 TLFDHLRRQPENNTNSFQCAQCFKFFATKKLLKSHVVRH--VNCYKCTMCDMTCSSASSLTTHIR 281
            .|..|::.: .:....|:|..|.:.||..|.|::|.:.|  ...::|..||...|::|.|..||.
Frog   578 NLKTHVKTK-HSKEMPFKCDICLQTFADSKDLQAHAILHQESKSHQCLHCDHKSSNSSDLKRHII 641

  Fly   282 YRHLKDKPLKCSECDTRCVRESDLAKHVQIVHSKTVHQCEHPDCHYSVRTYTQMRRHFLEVHGNN 346
            ..|.||.|.||..|:....|.|:|.||......|.:|||.|  |.:.:.....:.||.|.|| ..
Frog   642 SVHTKDYPHKCEVCEKGFHRPSELKKHEAAHKGKKMHQCRH--CEFQIADPFVLSRHILSVH-TK 703

  Fly   347 PILYACHCCERFFKSGKSLSAHLMKKHGFRLPSGHKRFTYR------VDENGFYR 395
            .:.:.|..|::.|:....|..| ||.|     ||.|.:...      .|.:||.|
Frog   704 ELPFRCKRCKKGFRQQMELKKH-MKTH-----SGKKVYQCEYCEYNTTDASGFKR 752

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	4/16 (25%)
		C2H2 Zn finger	207..225	CDD:275368	4/17 (24%)
		C2H2 Zn finger	237..257	CDD:275368	7/19 (37%)
		C2H2 Zn finger	263..284	CDD:275368	8/20 (40%)
		C2H2 Zn finger	292..311	CDD:275368	7/18 (39%)
		C2H2 Zn finger	352..373	CDD:275368	7/20 (35%)
zfx	XP_002935227.1	Zfx_Zfy_act	71..395	CDD:368066
		zf-C2H2	410..432	CDD:333835	4/17 (24%)
		C2H2 Zn finger	412..435	CDD:275368	5/20 (25%)
		C2H2 Zn finger	443..463	CDD:275368	7/21 (33%)
		C2H2 Zn finger	478..498	CDD:275368	4/22 (18%)
		C2H2 Zn finger	509..530	CDD:275368	4/27 (15%)
		COG5048	534..>789	CDD:227381	68/237 (29%)
		C2H2 Zn finger	538..558	CDD:275368	5/21 (24%)
		C2H2 Zn finger	566..587	CDD:275368	4/21 (19%)
		C2H2 Zn finger	595..615	CDD:275368	7/19 (37%)
		C2H2 Zn finger	623..644	CDD:275368	8/20 (40%)
		C2H2 Zn finger	652..701	CDD:275368	16/50 (32%)
		C2H2 Zn finger	709..729	CDD:275368	7/20 (35%)
		C2H2 Zn finger	737..758	CDD:275368	4/16 (25%)
		C2H2 Zn finger	766..786	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910