DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17829 and si:ch211-222k6.1

DIOPT Version :9

Sequence 1:	NP_652054.1	Gene:	CG17829 / 47718	FlyBaseID:	FBgn0025635	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_021324960.1	Gene:	si:ch211-222k6.1 / 100034531	ZFINID:	ZDB-GENE-050208-649	Length:	674	Species:	Danio rerio

Alignment Length:	465	Identity:	109/465 - (23%)
Similarity:	161/465 - (34%)	Gaps:	128/465 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 NGHIGDHLEHYAKAQDDRGAHAEHTEHQCTWNSCDFRTENQVEFE----RHSYYHGYYLNLLLQ- 102
            ||..|:.||...|.||..|..:         .|..|::..:|.|.    ..|:.....|||.::
Zfish    24 NGETGEQLEAVEKHQDTHGQKS---------TSLSFQSRPEVHFTCPQCGKSFSCEQSLNLHMKF 79

  Fly   103 ----GKLECDL-------------HPEI---------PACTAPARLMEKLPA-----LGQN-FRC 135
                ...|||.             |.:|         ..|.....|.|:|..     .|:. |.|
Zfish    80 HRGTKPYECDQCDKIFTLKTNLNEHMKIHNVDMLYTCDQCGKSFLLKERLNKHLKIHTGEKPFTC 144

  Fly   136 GWTDCEREFVSIVEFQDHIVKHA------------LFEY-----DIQKTPEDERPKTMCNWAMCH 183
              ..|.:.|:......:||..|.            .|.|     |..|....|||......|...
Zfish   145 --DQCGKNFLHKGYLTEHIKIHTGEKPHTCDQCGKRFAYKGNLTDHMKVHTGERPYACDQCAKRF 207

  Fly   184 KHMGNKYRLIEHISTHSNKKQVACFHCGELFRTKTTLFDHLRRQPENNTNSFQCAQCFKFFATKK 248
            ||.||   ||||:..|:.::..:|..||:.|:.|..|.||:|  .......|.|.:|.:.:..|:
Zfish   208 KHKGN---LIEHVKIHTGERPYSCDQCGKKFKLKHILSDHMR--IHTGEKPFTCEKCGRSYTRKR 267

  Fly   249 LLKSHVVRH--VNCYKCTMCDMTCSSASSLTTHIRYRHLKDKPLKCSECDTRCVRESDLAKHVQI 311
            .|..|:..|  |..:.|..|..:.........|:| .|.:::|..|.:|....:|...|
Zfish   268 NLSDHMKSHTGVKLHTCDQCGKSFVKTGVFKVHLR-THSRERPFNCDQCGKDFLRMGTL------ 325

  Fly   312 VHSKTVHQCEHPD-----CHYSVRTYTQMRRHFLEVH-----GNNPILYACHCCERFFKSGKSLS 366
                .|||..|..     |....:|:  .|...|:||     |..|  :.|..||:.||     .
Zfish   326 ----KVHQKRHSGIKDHICSECGKTF--FRDSELKVHQSVHTGEKP--FKCSHCEKTFK-----R 377

  Fly   367 AHLMKKHGFRLPSGH---------KRFTYRVDENGFYRLETTRLESLEVTQQILSPQVNDSLAKP 422
            |..||.|. ::.:|.         |:|.::.:.|...: ..||::.....|
Zfish   378 AEYMKMHR-KIHTGEKPYECEKCGKKFRHKGNFNDHVK-NHTRIKPFSCDQ-------------- 426

  Fly   423 GTGSCYEIVD 432
             .|.|:.:.|
Zfish   427 -CGKCFRLKD 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17829	NP_652054.1	C2H2 Zn finger	182..199	CDD:275368	8/16 (50%)
		C2H2 Zn finger	207..225	CDD:275368	8/17 (47%)
		C2H2 Zn finger	237..257	CDD:275368	5/19 (26%)
		C2H2 Zn finger	263..284	CDD:275368	4/20 (20%)
		C2H2 Zn finger	292..311	CDD:275368	4/18 (22%)
		C2H2 Zn finger	352..373	CDD:275368	8/20 (40%)
si:ch211-222k6.1	XP_021324960.1	C2H2 Zn finger	60..80	CDD:275368	4/19 (21%)
		C2H2 Zn finger	88..108	CDD:275368	3/19 (16%)
		C2H2 Zn finger	116..136	CDD:275368	4/19 (21%)
		C2H2 Zn finger	144..164	CDD:275368	5/21 (24%)
		zf-H2C2_2	156..181	CDD:316026	4/24 (17%)
		C2H2 Zn finger	172..192	CDD:275368	4/19 (21%)
		COG5048	196..607	CDD:227381	70/282 (25%)
		C2H2 Zn finger	200..220	CDD:275368	9/22 (41%)
		C2H2 Zn finger	228..248	CDD:275368	9/21 (43%)
		C2H2 Zn finger	256..276	CDD:275368	5/19 (26%)
		C2H2 Zn finger	284..304	CDD:275368	4/20 (20%)
		C2H2 Zn finger	312..332	CDD:275368	7/29 (24%)
		C2H2 Zn finger	340..360	CDD:275368	6/21 (29%)
		C2H2 Zn finger	368..388	CDD:275368	9/25 (36%)
		C2H2 Zn finger	396..416	CDD:275368	3/20 (15%)
		C2H2 Zn finger	424..444	CDD:275368	4/27 (15%)
		C2H2 Zn finger	452..472	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
		C2H2 Zn finger	508..528	CDD:275368
		C2H2 Zn finger	536..556	CDD:275368
		C2H2 Zn finger	564..584	CDD:275368
		C2H2 Zn finger	592..612	CDD:275368
		C2H2 Zn finger	620..640	CDD:275368
		C2H2 Zn finger	648..666	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910