Protein Alignment NEUROG1 and net

DIOPT Version :10

• Sequence 1: NP_006152.2
• Gene: NEUROG1 / 4762
• HGNCID: 7764
• Length: 237
• Species: Homo sapiens
• Sequence 2: NP_524820.2
• Gene: net / 45339
• FlyBaseID: FBgn0002931
• Length: 360
• Species: Drosophila melanogaster
• Alignment Length: 450
• Identity: 88/450 - (19%)
• Similarity: 142/450 - (31%)
• Gaps: 185/450 - (41%)

Human    80 WPPKRDALREQSNPSPSQDT---DGVKTTKVAHSMRNLQNGQLPSSTPASSGSRAFHRLSRRRSK 141
            |.|    :..:.:|.|:.:|   :||:         .:...:||||..||
  Fly   101 WEP----VAGKPSPKPAAETGEENGVE---------EVSRIKLPSSVFAS--------------- 137

Human   142 DVEFQDGWPRSPGRAFLPLRHRSSSEITLSECDVEEPGDPRGTRHPGVLPLFREYGSTSSIDVQG 206
            :.|.:||            ..:.::|:|..         ||....|.|:....|
  Fly   138 EFEEKDG------------LMKKAAEVTRG---------PRPDWDPDVVAALDE----------- 170

Human   207 VPEQSFFDILNEFRSEQPEARGSQNLRELLQVDPGALSGGSCGTKG----DPRNGQPTKDSLQSL 267
                       :|....|:.:...|..| |.:.|||  ||.....|    |...|:...||.:
  Fly   171 -----------DFDFNNPDNQLEDNFME-LAMQPGA--GGDEDDDGEDWFDEEGGEHEFDSDE-- 219

Human   268 QPLKEKEKSRKKPVRGLGSGDTVDSSIFRKLRSSKPEGEVGRPLGETEESRSPPEASRPWVCQKS 332
               .|.:.|..:...|||..|                ...||     ||::|            .
  Fly   220 ---MEGDYSDTEERDGLGPLD----------------DRYGR-----EETKS------------R 248

Human   333 FAHFDVQSMLFDLNEAAANRVSVAQRRNTTTGASAASAASAMVTLTASRAHSLGTLDPAFTSTED 397
            |..:.:.|.:...||                          .:||...|      .:..|...:|
  Fly   249 FTEYSMSSSVIRRNE--------------------------QLTLLDDR------FEKFFEQYDD 281

Human   398 -----LNCKENLEQDLGDDNSNDLLLSC-PHFRNE----IGGERERNVSFSRASVGSPGGSSEAH 452
                 |:|:| :|..:  |.::|:||.| ..|:.|    ...|.|:.....|.:......|.|..
  Fly   282 PEVGPLDCEE-IEGHV--DPNDDVLLRCAAEFKRERDAVYDAEYEKQWIRERLTQLQDDNSEEEE 343

Human   453 MA-------------EPTLSTHRTNASI----SVLEVPKEQQRTQSRPRQYSIEHVDLGA 495
            :|             |..|||:   ::|    .:::.||:.::....|:....|:| |||
  Fly   344 VAMQVEDGEQKKWDCESILSTY---SNIYNHPKLIQEPKKTRKILINPKTGLPENV-LGA 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEUROG1	NP_006152.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..83		1/2 (50%)
		bHLH_TS_NGN1_NeuroD3	82..153	CDD:381559	15/73 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	175..209		5/33 (15%)
net	NP_524820.2	bHLH_TS_ATOH8	262..329	CDD:381427	20/101 (20%)