DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NEUROG1 and Fer3

DIOPT Version :9

Sequence 1:	NP_006152.2	Gene:	NEUROG1 / 4762	HGNCID:	7764	Length:	237	Species:	Homo sapiens
Sequence 2:	NP_524322.1	Gene:	Fer3 / 41411	FlyBaseID:	FBgn0037937	Length:	195	Species:	Drosophila melanogaster

Alignment Length:	120	Identity:	43/120 - (35%)
Similarity:	56/120 - (46%)	Gaps:	25/120 - (20%)

- Green bases have known domain annotations that are detailed below.

Human    44 PPAPARRGAPNISRASEVPGAQDDEQERRRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNL 108
            |..|:..|..|.|.:|.             ::.|.||.|.|        :|..||.|||.||.||
  Fly    59 PQRPSTNGRANGSSSSS-------------KKTRRRVASMA--------QRRAANIRERRRMFNL 102

Human   109 NAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGLPGGGARER 163
            |.|.|.||..:|:|..:.:|::|||||.|..||..:||.|    .|.|....:.|
  Fly   103 NEAFDKLRRKVPTFAYEKRLSRIETLRLAITYIGFMAELL----SGTPSNSHKSR 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NEUROG1	NP_006152.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	35..83		9/38 (24%)
		HLH	90..149	CDD:238036	28/58 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	175..209
Fer3	NP_524322.1	HLH	87..135	CDD:278439	24/47 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910