Protein Alignment NEUROG1 and twi

DIOPT Version :10

• Sequence 1: NP_006152.2
• Gene: NEUROG1 / 4762
• HGNCID: 7764
• Length: 237
• Species: Homo sapiens
• Sequence 2: NP_523816.2
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Alignment Length: 185
• Identity: 56/185 - (30%)
• Similarity: 75/185 - (40%)
• Gaps: 47/185 - (25%)

Human    15 ASSSGSDLSG------FLTDEEDCARLQQAASASGPP--APARRGAPNISRASEVPGAQDDEQER 71
            |.||.|||:|      .|.|:.....|...:.|.|..  .|.||                    .
  Fly   303 ALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKPRRR--------------------L 347

Human    72 RRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRF 136
            :|:..:|....|.      .::||.||.|||.|..:||.|..:|:.::|:.|.| ||:||:||:.
  Fly   348 KRKPSKTEETDEF------SNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSD-KLSKIQTLKL 405

Human   137 AYNYIWALAETLRLADQGLPGGGARERLLPPQCVPCLPGPPSPASDAESWGSGAA 191
            |..||..|...|..:|..|      .:.|..|      |.||....|.|..|.||
  Fly   406 ATRYIDFLCRMLSSSDISL------LKALEAQ------GSPSAYGSASSLLSAAA 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEUROG1	NP_006152.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..83		8/49 (16%)
		bHLH_TS_NGN1_NeuroD3	82..153	CDD:381559	27/70 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	175..209		8/17 (47%)
twi	NP_523816.2	bHLH_TS_TWIST	363..421	CDD:381470	26/58 (45%)