Protein Alignment Gpo1 and GUT2

DIOPT Version :9

• Sequence 1: NP_001097332.1
• Gene: Gpo1 / 47611
• FlyBaseID: FBgn0022160
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_012111.1
• Gene: GUT2 / 854651
• SGDID: S000001417
• Length: 649
• Species: Saccharomyces cerevisiae
• Alignment Length: 653
• Identity: 272/653 - (41%)
• Similarity: 385/653 - (58%)
• Gaps: 76/653 - (11%)

  Fly     8 FGVT---AASACVGSVLASYTLDRWNT-----PHVVNNATVPPKRKRTLPP---RADQIKSLMSG 61
            |.||   ||.|......|:.|| .|.|     |.|.|:.:...:.....||   |.|.:..|...
Yeast     2 FSVTRRRAAGAAAAMATATGTL-YWMTSQGDRPLVHNDPSYMVQFPTAAPPQVSRRDLLDRLAKT 65

  Fly    62 EEFDVLIIGGGATGAGCALDSVTRGLKTALVELDDFASGTSSRSTKLIHGGVRYLQKAILGLDLE 126
            .:||||||||||||.|||||:.||||..||||..||||||||:|||:||||||||:||.......
Yeast    66 HQFDVLIIGGGATGTGCALDAATRGLNVALVEKGDFASGTSSKSTKMIHGGVRYLEKAFWEFSKA 130

  Fly   127 QYRMVKEALAERATMLESAPHLTHPLPIMLPVYTWWQVPYYWVGIKAYDLVAGDRNVKSSYYLSK 191
            |..:|.|||.||..::.:||||...|||::|:|:.|||||.::|.|.||..||.:|:|.||.|||
Yeast   131 QLDLVIEALNERKHLINTAPHLCTVLPILIPIYSTWQVPYIYMGCKFYDFFAGSQNLKKSYLLSK 195

  Fly   192 KDALELFPMLKKDKLCGAIVYYDGQQDDARMCLAVALTAARHGATVCNHVEVKELLKKDDGTGKQ 256
            ...:|..|||..|.|..::||:||..:|:|:...:|:||..:||||.|:|||::|: ||..:||.
Yeast   196 SATVEKAPMLTTDNLKASLVYHDGSFNDSRLNATLAITAVENGATVLNYVEVQKLI-KDPTSGKV 259

  Fly   257 VLCGAKVKDHISGKEFTVKAKCIVNAAGPFTDSIRKMD-NPT------------VKS-------- 300
            :  ||:.:|..:.:...:.|||:|||.||::|:|.:|| ||:            :||
Yeast   260 I--GAEARDVETNELVRINAKCVVNATGPYSDAILQMDRNPSGLPDSPLNDNSKIKSTFNQIAVM 322

  Fly   301 ---ICCPSSGVHIVLPGYYSPDQMGLLDPSTSDGRVIFFLPWQRQTIAGTTDLPC-EITHNPTPT 361
               :..||.|||||||.:|.|..|||||..||||||:||||||.:.:|||||:|. ::..||.||
Yeast   323 DPKMVIPSIGVHIVLPSFYCPKDMGLLDVRTSDGRVMFFLPWQGKVLAGTTDIPLKQVPENPMPT 387

  Fly   362 EDEIQFILNEIKNYLNADVEVRRGDVLSAWSGIRPLVSDPNK--------DDTQSLARNHIVHVS 418
            |.:||.||.|:::|:  :..|:|.||||||:|:||||.||..        ..||.:.|:|.:..|
Yeast   388 EADIQDILKELQHYI--EFPVKREDVLSAWAGVRPLVRDPRTIPADGKKGSATQGVVRSHFLFTS 450

  Fly   419 PSNLITIAGGKWTTYRAMAEHTIDAAIKA---CNLKPERAEAVTSYLKIEGGQGWTPTMYIRLVQ 480
            .:.|||||||||||||.|||.|:|..::.   .||||    ..|..:|:.|.:.||......|.|
Yeast   451 DNGLITIAGGKWTTYRQMAEETVDKVVEVGGFHNLKP----CHTRDIKLAGAEEWTQNYVALLAQ 511

  Fly   481 DFGLECEVAQHLAKSYGDRAFAVSKM----------ASLTGKRWPII-----GNRIHPE---FPY 527
            ::.|..:::.:|.::||.|:..:.:.          .||..|...:|     .|.::.:   :|:
Yeast   512 NYHLSSKMSNYLVQNYGTRSSIICEFFKESMENKLPLSLADKENNVIYSSEENNLVNFDTFRYPF 576

  Fly   528 IDAEIRYGVR-EYACTAVDMIARRLRLAFLNVQAAQEALPVIVDIMGEELGWSKDEKERQIKHAT 591
            ...|::|.:: ||..|.:|.:.||.|.|||:.:.|..|:...|.:||:|..||:.:::.:::...
Yeast   577 TIGELKYSMQYEYCRTPLDFLLRRTRFAFLDAKEALNAVHATVKVMGDEFNWSEKKRQWELEKTV 641

  Fly   592 EFL 594
            .|:
Yeast   642 NFI 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gpo1	NP_001097332.1	PLN02464	9..594	CDD:215257	270/650 (42%)
		DAO_C	458..583	CDD:293506	38/143 (27%)
		EFh	624..684	CDD:238008
		EF-hand_7	624..683	CDD:290234
GUT2	NP_012111.1	GlpA	84..649	CDD:223651	238/570 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341934
Domainoid	1	1.000	377	1.000	Domainoid score	I111
eggNOG	1	0.900	-	-		E1_COG0578
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	455	1.000	Inparanoid score	I244
Isobase	1	0.950	-	0	Normalized mean entropy	S668
OMA	1	1.010	-	-		QHG53921
OrthoFinder	1	1.000	-	-		FOG0002536
OrthoInspector	1	1.000	-	-		otm46478
orthoMCL	1	0.900	-	-		OOG6_101157
Panther	1	1.100	-	-	LDO	PTHR11985
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R509
SonicParanoid	1	1.000	-	-		X1659
TreeFam	1	0.960	-	-
	15	14.740