DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gpo1 and SDP6

DIOPT Version :9

Sequence 1:	NP_001097332.1	Gene:	Gpo1 / 47611	FlyBaseID:	FBgn0022160	Length:	724	Species:	Drosophila melanogaster
Sequence 2:	NP_187648.1	Gene:	SDP6 / 820199	AraportID:	AT3G10370	Length:	629	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	285/570 - (50%)
Similarity:	386/570 - (67%)	Gaps:	33/570 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 TLPPRADQIKSLM---SGEEFDVLIIGGGATGAGCALDSVTRGLKTALVELDDFASGTSSRSTKL 108
            ::|.|:.|..:|:   :.:..|||:|||||||:|.|||:|||||:..|||.:||:||||||||||
plant    54 SVPSRSAQESALIAATASDPLDVLVIGGGATGSGVALDAVTRGLRVGLVEREDFSSGTSSRSTKL 118

  Fly   109 IHGGVRYLQKAILGLDLEQYRMVKEALAERATMLESAPHLTHPLPIMLPVYTWWQVPYYWVGIKA 173
            ||||||||:||:..||..|.::|..||.||..::|:||||.|.||.|.|.:.|::|.|:|:|:|.
plant   119 IHGGVRYLEKAVFNLDYGQLKLVFHALEERKQLIENAPHLCHALPCMTPCFDWFEVIYFWMGLKM 183

  Fly   174 YDLVAGDRNVKSSYYLSKKDALELFPMLK---KDK-LCGAIVYYDGQQDDARMCLAVALTAARHG 234
            ||||||.|.:..|.|.|.|:::||||.|.   ||| |.|.:||||||.:|:|:.:.:|.|||..|
plant   184 YDLVAGPRLLHLSRYYSAKESIELFPTLARKGKDKNLRGTVVYYDGQMNDSRLNVGLACTAALAG 248

  Fly   235 ATVCNHVEVKELLKKDDGTGKQVLCGAKVKDHISGKEFTVKAKCIVNAAGPFTDSIRKMDNPTVK 299
            |.|.||.||..|: .||.| |::: ||:::::::|:||...||.:|||||||.||||||.:...|
plant   249 AAVLNHAEVVSLI-TDDAT-KRII-GARIRNNLTGQEFNSYAKVVVNAAGPFCDSIRKMIDEDTK 310

  Fly   300 SICCPSSGVHIVLPGYYSPDQMGLLDPSTSDGRVIFFLPWQRQTIAGTTDLPCEITHNPTPTEDE 364
            .:.|||||||||||.||||:.|||:.|.|.||||:|.|||..:|:|||||....||..|.|.|||
plant   311 PMICPSSGVHIVLPDYYSPEGMGLIVPKTKDGRVVFMLPWLGRTVAGTTDSNTSITSLPEPHEDE 375

  Fly   365 IQFILNEIKNYLNADVEVRRGDVLSAWSGIRPLVSDPNKDDTQSLARNHIVHVSPSNLITIAGGK 429
            |||||:.|.:|||  ::|||.||||||||||||..||....|:|::|:|:|......|:||.|||
plant   376 IQFILDAISDYLN--IKVRRTDVLSAWSGIRPLAMDPTAKSTESISRDHVVFEENPGLVTITGGK 438

  Fly   430 WTTYRAMAEHTIDAAIKACNLKPERAEAVTSYLKIEGGQGWTPT-------MYIRLVQDFG---- 483
            |||||:|||..:|||||:..|||.. |.||..|::.|..||.|:       .|:|:.:.:|
plant   439 WTTYRSMAEDAVDAAIKSGQLKPTN-ECVTQKLQLLGSYGWEPSSFTTLAQQYVRMKKTYGGKVV 502

  Fly   484 ---LECEVAQHLAKSYGDRAFAVSKMASLTGKRWPIIGNRIHPEFPYIDAEIRYGVR-EYACTAV 544
               ::...|:||:.:||..|..|:.:|...|     :|.|:....|:::||:.|..| ||..:||
plant   503 PGAMDTAAAKHLSHAYGSMADRVATIAQEEG-----LGKRLAHGHPFLEAEVAYCARHEYCESAV 562

  Fly   545 DMIARRLRLAFLNVQAAQEALPVIVDIMGEELGWSKDEKERQIKHATEFL 594
            |.||||.|:|||:..||..||..:|:|:..|..|.|..::::::.|.|||
plant   563 DFIARRCRIAFLDTDAAARALQRVVEILASEHKWDKSRQKQELQKAKEFL 612

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gpo1	NP_001097332.1	PLN02464	9..594	CDD:215257	283/568 (50%)
		DAO_C	458..583	CDD:293506	48/139 (35%)
		EFh	624..684	CDD:238008
		EF-hand_7	624..683	CDD:290234
SDP6	NP_187648.1	PLN02464	1..629	CDD:215257	285/570 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	421	1.000	Domainoid score	I120
eggNOG	1	0.900	-	-		E1_COG0578
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H352
Inparanoid	1	1.050	526	1.000	Inparanoid score	I286
OMA	1	1.010	-	-		QHG53921
OrthoDB	1	1.010	-	-		D669193at2759
OrthoFinder	1	1.000	-	-		FOG0002536
OrthoInspector	1	1.000	-	-		otm3359
orthoMCL	1	0.900	-	-		OOG6_101157
Panther	1	1.100	-	-	LDO	PTHR11985
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1659
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840