Protein Alignment Gpo1 and Gpd2

DIOPT Version :10

• Sequence 1: NP_611063.1
• Gene: Gpo1 / 47611
• FlyBaseID: FBgn0022160
• Length: 724
• Species: Drosophila melanogaster
• Sequence 2: NP_036868.1
• Gene: Gpd2 / 25062
• RGDID: 2726
• Length: 727
• Species: Rattus norvegicus
• Alignment Length: 687
• Identity: 438/687 - (63%)
• Similarity: 544/687 - (79%)
• Gaps: 19/687 - (2%)

  Fly    46 RTLPPRADQIKSLMSGEEFDVLIIGGGATGAGCALDSVTRGLKTALVELDDFASGTSSRSTKLIH 110
            |..|.|..|:.:|.:..|||:|:|||||||.|||||:|||||||||||.:|||||||||||||||
  Rat    52 REPPSREAQLMTLQNTSEFDILVIGGGATGCGCALDAVTRGLKTALVERNDFASGTSSRSTKLIH 116

  Fly   111 GGVRYLQKAILGLDLEQYRMVKEALAERATMLESAPHLTHPLPIMLPVYTWWQVPYYWVGIKAYD 175
            ||||||||||..||:||||||||||.|||.:||.||||:.|||||||:|.|||:||||||||.||
  Rat   117 GGVRYLQKAITNLDVEQYRMVKEALHERANLLEIAPHLSAPLPIMLPLYKWWQLPYYWVGIKMYD 181

  Fly   176 LVAGDRNVKSSYYLSKKDALELFPMLKKDKLCGAIVYYDGQQDDARMCLAVALTAARHGATVCNH 240
            ||||...:||||.|||..|||.||||:||||.|||||||||.:||||.||:||||||:||...|:
  Rat   182 LVAGSHCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANY 246

  Fly   241 VEVKELLKK-DDGTGKQVLCGAKVKDHISGKEFTVKAKCIVNAAGPFTDSIRKMDNPTVKSICCP 304
            :||..|||| |..|||:.:.||:.||.::|.||.|:|||::||.||||||:||||:..|..||.|
  Rat   247 MEVVSLLKKTDPETGKERVSGARCKDVLTGHEFNVRAKCVINATGPFTDSVRKMDDNDVVPICQP 311

  Fly   305 SSGVHIVLPGYYSPDQMGLLDPSTSDGRVIFFLPWQRQTIAGTTDLPCEITHNPTPTEDEIQFIL 369
            |:|||||:||||||:.||||||:||||||||||||::.|||||||.|.::||:|.|:||:|.|||
  Rat   312 SAGVHIVMPGYYSPENMGLLDPATSDGRVIFFLPWEKMTIAGTTDSPTDVTHHPIPSEDDINFIL 376

  Fly   370 NEIKNYLNADVEVRRGDVLSAWSGIRPLVSDPNKDDTQSLARNHIVHVSPSNLITIAGGKWTTYR 434
            ||::|||:.||||||||||:|||||||||:||...:|||::|||:|.||.|.|||||||||||||
  Rat   377 NEVRNYLSCDVEVRRGDVLAAWSGIRPLVTDPKSANTQSISRNHVVEVSDSGLITIAGGKWTTYR 441

  Fly   435 AMAEHTIDAAIKACNLK--PERAEAVTSYLKIEGGQGWTPTMYIRLVQDFGLECEVAQHLAKSYG 497
            :|||.|::.|:|..||.  |.|    |..|.::||:.|:||:|||||||:|||.||||||||:||
  Rat   442 SMAEDTVNKAVKLHNLNAGPSR----TVGLFLQGGKDWSPTLYIRLVQDYGLESEVAQHLAKTYG 502

  Fly   498 DRAFAVSKMASLTGKRWPIIGNRIHPEFPYIDAEIRYGVREYACTAVDMIARRLRLAFLNVQAAQ 562
            |:||.|:||||:||||||::|.|:..|||||:||::||::||||||||||:||.||||||||||:
  Rat   503 DKAFDVAKMASVTGKRWPVVGVRLVSEFPYIEAEVKYGIKEYACTAVDMISRRTRLAFLNVQAAE 567

  Fly   563 EALPVIVDIMGEELGWSKDEKERQIKHATEFLANEMGHSVNRTSK--ERIPIKLSKEEIQTYIKR 625
            ||||.||::||.||.||:..|:.:::.||.||..|||:. :||.:  :...|.|...:|..|.||
  Rat   568 EALPKIVELMGRELNWSELRKQEELETATRFLYYEMGYK-SRTEQLTDSTEISLLPPDIDRYKKR 631

  Fly   626 FQLIDKDKKGYVSINDIRRALKSFGDGDVSGEQLHEILREIDTNMNGQVELDEYLQMMSAIKTGD 690
            |.:.|:|:||:::|.|::|.|:|. :..:..:.|||||.|:|.|.||||||.|:||:|||:.||.
  Rat   632 FHMFDEDEKGFITIVDVQRVLESI-NVQMDEDTLHEILCEVDLNKNGQVELHEFLQLMSAVHTGR 695

  Fly   691 VAYSRFARMAELEEQKHEAANLKQ---ISVDRSGGGL 724
            |:.||.|.:.:..|:     ||.:   |.||||.|||
  Rat   696 VSGSRLAILMKTAEE-----NLDRRVPIPVDRSCGGL 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gpo1	NP_611063.1	DAO	9..594	CDD:477422	378/550 (69%)
		EFh	624..684	CDD:238008	29/59 (49%)
Gpd2	NP_036868.1	DAO	1..599	CDD:477422	378/550 (69%)
		EFh	627..689	CDD:238008	30/62 (48%)