DRSC/TRiP Functional Genomics Resources

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Protein Alignment NEUROD2 and dimm

DIOPT Version :9

Sequence 1:NP_006151.3 Gene:NEUROD2 / 4761 HGNCID:7763 Length:382 Species:Homo sapiens
Sequence 2:NP_001260674.1 Gene:dimm / 35404 FlyBaseID:FBgn0023091 Length:390 Species:Drosophila melanogaster


Alignment Length:269 Identity:79/269 - (29%)
Similarity:108/269 - (40%) Gaps:82/269 - (30%)


- Green bases have known domain annotations that are detailed below.


Human   107 KKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIW 171
            ::||......||: :||.::|.|||.|||.||.|..:||:|:|.....::|||||||.||||||.
  Fly   143 RRRKGALNAKERN-MRRLESNERERMRMHSLNDAFQSLREVIPHVEMERRLSKIETLTLAKNYII 206

Human   172 ALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADG----AGRFHGSGG 232
            .|:.|:.| ||                   |..|..|:|||       ||.|    :.....|||
  Fly   207 NLTHIILS-KR-------------------NEEAAALELNS-------GAVGGVLLSNLSSESGG 244

Human   233 PFAMHPYPYPCSRLAGAQC----QAAGGLGGGAAHALRTHGYCAAYETLYAAAGGGG-------- 285
            |.|.   ..|.:..|...|    .|:||                |::....||..|.        
  Fly   245 PVAS---GIPANSNAATICFEDTLASGG----------------AFDCAILAATDGSLLNAATVT 290

Human   286 ASPDYNSSEYEG-PLSPPLCLNGNFSLKQDSS--PDHEKSYHYSMHYSA-----------LPGSR 336
            .||...|.:.:. .|..|:     ...:|.:|  |.|:::.|...|..|           |.|:.
  Fly   291 TSPAMQSIQSQAIHLQTPM-----EQQQQQASHLPHHQQAMHGHGHLGASIQSQQQPSLVLNGTT 350

Human   337 PTGHGLVFG 345
            ..|.|:..|
  Fly   351 SVGLGIGIG 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NEUROD2NP_006151.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..129 7/21 (33%)
bHLH_TS_NeuroD2 88..180 CDD:381563 35/72 (49%)
Nuclear localization signal. /evidence=ECO:0000255 107..113 2/5 (40%)
Neuro_bHLH 180..310 CDD:403655 31/146 (21%)
dimmNP_001260674.1 HLH 154..208 CDD:238036 30/54 (56%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3898
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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