DRSC/TRiP Functional Genomics Resources

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Protein Alignment NEUROD1 and tap

DIOPT Version :9

Sequence 1:NP_002491.3 Gene:NEUROD1 / 4760 HGNCID:7762 Length:356 Species:Homo sapiens
Sequence 2:NP_524124.1 Gene:tap / 39935 FlyBaseID:FBgn0015550 Length:398 Species:Drosophila melanogaster


Alignment Length:305 Identity:93/305 - (30%)
Similarity:125/305 - (40%) Gaps:64/305 - (20%)


- Green bases have known domain annotations that are detailed below.


Human    14 PQPQGPPSWTDECLSS----------QDEEHEADKKEDDLETMNAEEDSLRNGGEEEDEDEDLEE 68
            |||....:|....|||          ....|........:|.:|:.   ..||    ..|..|..
  Fly    57 PQPYSGGTWDAVPLSSPPAGFVGLLDTSSNHSTRSGRTLVEHLNSR---ATNG----VFDPPLTS 114

Human    69 EEEEEEEDDD-QKPKRR-GPKKKKMTKAR-------LERFKLRRMKANARERNRMHGLNAALDNL 124
            ...:..||.: .:|||: ...|.::|::|       ::||  ||||||.|||||||.||.||:.|
  Fly   115 TPVKSPEDPNAPRPKRKYAVGKNRVTRSRSPTQVVKIKRF--RRMKANDRERNRMHNLNDALEKL 177

Human   125 RKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSGKS--PDLVSFVQTLCKGLSQPTTNLVAGC 187
            |..:|...:..||:|||.||.|.|||:||.::|.||.|  .||.........|  :..|..:...
  Fly   178 RVTLPSLPEETKLTKIEILRFAHNYIFALEQVLESGGSINLDLEKLQNFTLSG--ERITKELFDA 240

Human   188 LQLNPRTF-----LPEQNQDMPP---HLPTASASFPVHP-----------YSYQSPGLPSPPYGT 233
            |.:||:.:     :....|.|.|   | .||.||....|           |..|.||....  |:
  Fly   241 LFVNPQPYPLFGRMFPYGQGMAPLAQH-QTAPASHAEQPPAMGGFQHGMDYPQQPPGFDFT--GS 302

Human   234 MDSSH--------VFHVKPPPHAYSAALEPFFESPLTDCTSPSFD 270
            |...|        ..|::|.|...|:..:  |.....|....|||
  Fly   303 MRFYHQQQQQPHQPHHLQPNPQQESSPQQ--FSQEKYDLFRGSFD 345

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NEUROD1NP_002491.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..94 21/91 (23%)
bHLH_TS_NeuroD1 75..160 CDD:381562 44/93 (47%)
Nuclear localization signal. /evidence=ECO:0000255 87..93 1/5 (20%)
Neuro_bHLH 160..284 CDD:403655 34/140 (24%)
tapNP_524124.1 HLH 155..207 CDD:278439 32/51 (63%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165145433
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3898
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.740

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