Protein Alignment aPKC and Prkcq

DIOPT Version :9

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_001263650.1
• Gene: Prkcq / 85420
• RGDID: 620968
• Length: 707
• Species: Rattus norvegicus
• Alignment Length: 583
• Identity: 203/583 - (34%)
• Similarity: 282/583 - (48%)
• Gaps: 132/583 - (22%)

  Fly   482 YRRGARRWRKLYRVNGHIFQAKRFNRRAFCAYCQDRIWGLGRQGFKCIQCKLLVHKKCHKLVQKH 546
            :||||.:..|::.|..|.|.|..|.:..||:.|.:.:|||.:||::|.||...:||||...|...
  Rat   144 HRRGAIKQAKVHHVKCHEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAK 208

  Fly   547 CT------------------DQP------------------------------------------ 551
            ||                  |.|
  Rat   209 CTGSAINSRETMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRC 273

  Fly   552 ----------------------------------EPLVKERAEESSDPIPV------PLPPLP-- 574
                                              |.:.:|...|.|.|..:      |..|.|
  Rat   274 QTKVANLCGINQKLMAEALAMIESTQQARTLRDSEHIFREGPIEISFPRSIKSETRPPCVPTPGK 338

  Fly   575 -------YEAMSGGAEACETHDHAHIVAPPPPEDPLEPGT-QRQYSLNDFELIRVIGRGSYAKVL 631
                   :|:...||:        ....||.||..|:..: |.:..::||.|.:::|:||:.||.
  Rat   339 KEPQGICWESPLDGAD--------KTAQPPEPEVNLQRASLQLKLKIDDFILHKMLGKGSFGKVF 395

  Fly   632 MVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEF 696
            :.|.:||::.:|:|.:||.:|..|:|::....||.|...|..||||..:...|||...||||:|:
  Rat   396 LAEFKRTKQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQTKENLFFVMEY 460

  Fly   697 VRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGM 761
            :.|||||||:|...:.....|.||||||.|.|.|||.|||:||||||||:|||.:||||:.|:||
  Rat   461 LNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLDRDGHIKIADFGM 525

  Fly   762 CKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQ 826
            |||.:.....|:||||||:|||||||.|:.|..|||||:.||||||||.|:|||         ..
  Rat   526 CKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPF---------HG 581

  Fly   827 NTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWEL 891
            ..|:.||..|.......||.|...|..:|.....:.|..|||...     ||..||.|:.::||.
  Rat   582 QDEEELFHSIRMDNPFYPRWLEREAKDLLVKLFVREPEKRLGVRG-----DIRQHPLFREINWEE 641

  Fly   892 LERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQLTPDDDHVIDNIDQSEFEGFEYVNPLLMSL 954
            ||||::.|||:|::.|..|.:||..||..|..:|:..|..:|:::||:.|..|.::||.:.:|
  Rat   642 LERKEIDPPFRPKVKSPYDCSNFDKEFLSEKPRLSFADRALINSMDQNMFSNFSFINPGMETL 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556	22/69 (32%)
		S_TKc	616..884	CDD:214567	127/267 (48%)
		STKc_aPKC	620..947	CDD:270740	150/326 (46%)
Prkcq	NP_001263650.1	C1_1	160..212	CDD:278556	22/51 (43%)
		C1_1	232..284	CDD:278556	0/51 (0%)
		STKc_nPKC_theta	374..704	CDD:270770	155/343 (45%)
		S_TKc	380..634	CDD:214567	127/267 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D222529at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920