DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aPKC and AT3G44610

DIOPT Version :9

Sequence 1:	NP_001260984.1	Gene:	aPKC / 47594	FlyBaseID:	FBgn0261854	Length:	958	Species:	Drosophila melanogaster
Sequence 2:	NP_190047.2	Gene:	AT3G44610 / 823587	AraportID:	AT3G44610	Length:	451	Species:	Arabidopsis thaliana

Alignment Length:	434	Identity:	113/434 - (26%)
Similarity:	182/434 - (41%)	Gaps:	126/434 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   579 SGGAEACETHDHAHIVAPPP------PEDPLEPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRR 637
            |.|:.:..:   |..:.|.|      ....|.|..:...||:|......:|.|....|.:.|.:.
plant    29 SSGSRSSSS---AAALTPAPSAHGSFSSSKLPPSLRSSLSLSDLRFRLRLGSGDIGSVFLAEFKS 90

  Fly   638 TRRIYAMKVIK----KALVTDDEDI------DWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFF 692
            ...:.....:|    .|.|.|.:::      ...:||:.:.|:. :||||..|::...:|..|..
plant    91 LTAVTETTAVKLPLLAAKVMDKKELASRSKEGRAKTEREILESL-DHPFLPTLYAAIDSPKWLCL 154

  Fly   693 VIEFVRGGDLMYHMQRQ----RRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGH 753
            :.||..||||  |:.||    :|..|...|||.:|:.:|:.:||..||:|||||.:|||:..:||
plant   155 LTEFCPGGDL--HVLRQKQTHKRFHESAVRFYVSEVIVAIEYLHMLGIVYRDLKPENVLVRSDGH 217

  Fly   754 IKLTDYGM---CKE-------------------------GIRPGDTTSTFC-------------- 776
            |.|||:.:   |.|                         |:....|||:.|
plant   218 IMLTDFDLSLKCDESTSTPQIVLNRNNLPNGSSDQNENQGMDHRQTTSSSCMIPNCIVPAVSCFH 282

  Fly   777 --------------------------------GTPNYIAPEILRGEDYGFSVDWWALGVLLYEML 809
                                            ||..|:||||:.||.:|.:||||.||:.::|:.
plant   283 PRIRRRKKKTDHRNNGPELVAEPVDVRSMSFVGTHEYLAPEIVSGEGHGSAVDWWTLGIFMFELF 347

  Fly   810 AGRSPF-----DLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAAS--VLKGFLNKNPADRL 867
            .|.:||     :|..|:              |:.:.:..|:..::.:|:  ::...|.|:|:.||
plant   348 YGTTPFKGMDHELTLAN--------------IVARALEFPKEPTIPSAAKDLISQLLAKDPSRRL 398

  Fly   868 GCHRESAFMDIVSHPFFKNMDWELLERKQ---VTPPFKPRLDSD 908
            |....:.  .:..||||:.::|.||...:   :.|||:..|.||
plant   399 GSSLGAT--AVKRHPFFQGVNWALLMCTRPPFLPPPFRKELLSD 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556
		S_TKc	616..884	CDD:214567	92/362 (25%)
		STKc_aPKC	620..947	CDD:270740	103/387 (27%)
AT3G44610	NP_190047.2	PKc_like	71..424	CDD:304357	97/371 (26%)
AT3G44610	NP_190047.2	S_TKc	75..413	CDD:214567	92/356 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I1276
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050