DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aPKC and WAG2

DIOPT Version :9

Sequence 1:	NP_001260984.1	Gene:	aPKC / 47594	FlyBaseID:	FBgn0261854	Length:	958	Species:	Drosophila melanogaster
Sequence 2:	NP_188054.1	Gene:	WAG2 / 820658	AraportID:	AT3G14370	Length:	480	Species:	Arabidopsis thaliana

Alignment Length:	379	Identity:	111/379 - (29%)
Similarity:	172/379 - (45%)	Gaps:	91/379 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   613 LNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFL 677
            |...:|||.:|.|:..:|.:..||.:...:|:|||.:..:|.::.:..|:||..:. :..:||||
plant    85 LRHLKLIRHLGTGNLGRVFLCNLRDSSARFALKVIDRNCLTTEKKLSQVETEAEIL-SLLDHPFL 148

  Fly   678 VGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQ--RRLPEEHARFYAAEISLALNFLHEKGIIYRD 740
            ..|::..........:|::...|||...:::|  .|||.:..||:|||:.:||.:||..||:|||
plant   149 PTLYARIDESHYTCLLIDYAPNGDLHSLLRKQPGNRLPIQPVRFFAAEVLVALEYLHAMGIVYRD 213

  Fly   741 LKLDNVLLDHEGHIKLTDYGMC----------------------------------------KEG 765
            ||.:||||..:||:.|:|:.:|                                        :|.
plant   214 LKPENVLLREDGHVMLSDFDLCFKSDVVPTFKSRRYRRSSSSPSLRRRRSGCFSVAAEKKYEREE 278

  Fly   766 I------RPGDTTSTFC-GTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASEN 823
            |      .|....|..| ||..|:|||::.|..:|..|||||.|:.|||:|.|.:||    ..|:
plant   279 IVSEFAAEPVTAFSRSCVGTHEYLAPELVSGNGHGSGVDWWAFGIFLYELLYGTTPF----KGES 339

  Fly   824 PDQNTEDYLFQVILEKTIRIPRSLSV-------RAASVLKGFLNKNPADRLGCHRESAFMDIVSH 881
            .:|.         |...:...::.|.       .|..:::..|.|:|..||||.|.:  .||..|
plant   340 KEQT---------LRNIVSTTKTASFHMDGDLDEARDLIEKLLVKDPRKRLGCARGA--QDIKRH 393

  Fly   882 PFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQLT--PDDDHVI 933
            |||..:.|.|:..      :||           |.|..|..::.:  |...|||
plant   394 PFFDGIKWPLIRH------YKP-----------PEEVRGLVIKKSTRPHASHVI 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556
		S_TKc	616..884	CDD:214567	97/323 (30%)
		STKc_aPKC	620..947	CDD:270740	108/372 (29%)
WAG2	NP_188054.1	STKc_phototropin_like	86..420	CDD:270726	106/366 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I1276
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.050