Protein Alignment aPKC and prkcq

DIOPT Version :9

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: XP_009298659.1
• Gene: prkcq / 555521
• ZFINID: ZDB-GENE-041210-195
• Length: 719
• Species: Danio rerio
• Alignment Length: 592
• Identity: 205/592 - (34%)
• Similarity: 289/592 - (48%)
• Gaps: 142/592 - (23%)

  Fly   482 YRRGARRWRKLYRVNGHIFQAKRFNRRAFCAYCQDRIWGLGRQGFKCIQCKLLVHKKC-HKLVQK 545
            :||||.:..|::.|..|.|.|..|.:..||:.|::.:|||.:||::|.||...:|||| .|::.|
Zfish   150 HRRGAIKQAKVHVVKCHEFTATFFPQPTFCSVCKEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAK 214

  Fly   546 --------------------------------------HC------------------------- 547
                                                  ||
Zfish   215 CTGSAVNSKETMIHKERFKIDMPHRFKVYNYMSPTFCEHCGTLLWGLARQGLKCEECGMNVHHKC 279

  Fly   548 ---------------------------------------------TDQPEPLVKERAEESSDPIP 567
                                                         .|||..:.:.....:..|:
Zfish   280 QKKVANLCGVNQKLMAEALAMIESTQQQARSSRDTETVGREGPVSADQPGVIREPSGRLAISPL- 343

  Fly   568 VPLPPLP---YEAMSGGAEACETHDHAHIVAPPPPEDPLEP--GTQR----QYSLNDFELIRVIG 623
            .|.||||   ::.:|..:.|....        |..|:| ||  .|.|    :::::.|.|.:::|
Zfish   344 TPAPPLPRKEHQGISWDSPADGRR--------PSLEEP-EPLYATPRKEHHKFTIDSFILHKMLG 399

  Fly   624 RGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPS 688
            :||:.||.:.||:.:.:.:|:|.:||.:|..|:|::....|:.|...|.:||||..|:..|||..
Zfish   400 KGSFGKVFLAELKGSGQFFAVKALKKDVVLMDDDVECTMVERRVLSLAWDHPFLTHLYCTFQTKE 464

  Fly   689 RLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGH 753
            .||||:|::.|||||:|:|...|.....:.||||||...|.|||.|||:||||||||:|||.:||
Zfish   465 NLFFVMEYLNGGDLMFHIQTCHRFDLPRSTFYAAEIICGLQFLHSKGIVYRDLKLDNILLDTDGH 529

  Fly   754 IKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLA 818
            ||:.|:|||||.|.....|.||||||:|||||||.|:.||.|||||:.||||||||.|:|||
Zfish   530 IKIADFGMCKENIIGEARTCTFCGTPDYIAPEILLGQKYGTSVDWWSFGVLLYEMLIGQSPF--- 591

  Fly   819 GASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPF 883
                  ..:.|:.|||.|.......||.|:..|..:|.....:.|..|||...     :|..|||
Zfish   592 ------HGHDEEELFQSIRTDDPCYPRWLTRDARDILVKLFVREPERRLGVKG-----NIRQHPF 645

  Fly   884 FKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQLTPDDDHVIDNIDQSEFEGFEYVN 948
            |:..||..||.:||.|||||.:.|..|.:||..||..|..:|:..|..:|:::|||.||.|.::|
Zfish   646 FRETDWSALEERQVEPPFKPTVKSANDCSNFDKEFINEKPRLSVTDRMMINSMDQSMFENFSFIN 710

  Fly   949 PLLMSLE 955
            |::..|:
Zfish   711 PIMTRLK 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556	23/160 (14%)
		S_TKc	616..884	CDD:214567	126/267 (47%)
		STKc_aPKC	620..947	CDD:270740	153/326 (47%)
prkcq	XP_009298659.1	C1_1	166..218	CDD:278556	21/51 (41%)
		C1_1	238..290	CDD:278556	2/51 (4%)
		STKc_nPKC_theta	386..716	CDD:270770	157/343 (46%)
		S_TKc	392..646	CDD:214567	126/267 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D222529at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920