Protein Alignment aPKC and STK32B

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: XP_047271880.1
• Gene: STK32B / 55351
• HGNCID: 14217
• Length: 502
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 108/351 - (30%)
• Similarity: 183/351 - (52%)
• Gaps: 31/351 - (8%)

  Fly   569 PLPPLP---YEAMSGGAEACETHDHAHIVAPPPPEDPLEPGTQRQYSLNDFELIRVIGRGSYAKV 630
            |.|.:.   ::.:..|||..       |...|.|....|..|.|:::.:.|:::|.||:||:.||
Human    68 PRPSIANQIWDFLIAGAELV-------ISGSPRPSMDTEWNTFRRFNFDHFQILRAIGKGSFGKV 125

  Fly   631 LMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIE 695
            .:|:.|.|:::||||.:.|....:.:::..|..|..:.: ...|||||.|...||....:|.|::
Human   126 CIVQKRDTKKMYAMKYMNKQKCIERDEVRNVFRELQIMQ-GLEHPFLVNLWYSFQDEEDMFMVVD 189

  Fly   696 FVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYG 760
            .:.||||.||:|:.....|...:.|..|::|||.:|....||:||:|.||:|||..||:.:||:.
Human   190 LLLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFN 254

  Fly   761 MCKEGIRPGDTTSTFCGTPNYIAPEIL-----RGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGA 820
            :... ::..:..|:..||..|:|||:.     ||..|.:.||||:||:..||:|.|..|:::...
Human   255 IATV-VKGAERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRPYEIHSV 318

  Fly   821 SENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFK 885
            :      ..|.:..:...:.:....:......::|:..|.|:|..|:     |:..||.|.|:..
Human   319 T------PIDEILNMFKVERVHYSSTWCKGMVALLRKLLTKDPESRV-----SSLHDIQSVPYLA 372

  Fly   886 NMDWELLERKQVTPPFKP---RLDSD 908
            :|:|:.:.:|.:.|.|.|   ||:.|
Human   373 DMNWDAVFKKALMPGFVPNKGRLNCD 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	96/297 (32%)
STK32B	XP_047271880.1	STKc_Yank1	110..371	CDD:270730	88/273 (32%)