Protein Alignment aPKC and aurkb

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: XP_012809281.1
• Gene: aurkb / 549613
• XenbaseID: XB-GENE-1019626
• Length: 370
• Species: Xenopus tropicalis
• Alignment Length: 298
• Identity: 78/298 - (26%)
• Similarity: 156/298 - (52%)
• Gaps: 34/298 - (11%)

  Fly   608 QRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDW-----VQTEKHV 667
            :|:::::||::.|.:|:|.:..|.:...::.:.|.|:||:.|:.: :.|.::.     ::.:.|:
 Frog    95 KRKFTIDDFDIGRPLGKGKFGNVYLARDKQNKFIMALKVLFKSQL-EKEGVEHQLRREIEIQSHL 158

  Fly   668 FETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLH 732
                 .||.::.:::.|....|::.::||...|:|...:|:..|..|:.:..:..|::.||.:.|
 Frog   159 -----RHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALQYCH 218

  Fly   733 EKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVD 797
            |:.:|:||:|.:|:|:.::|.:|:.|:|.....  |.....|.|||.:|:.||::.|:.:...||
 Frog   219 ERKVIHRDIKPENLLMGYKGELKIADFGWSVHA--PSLRRRTMCGTLDYLPPEMIEGKTHDEKVD 281

  Fly   798 WWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKN 862
            .|..|||.:|.|.|..|||      :| .:||.:  :.|:...::.|..||..:..::...|..:
 Frog   282 LWCAGVLCFEFLVGMPPFD------SP-SHTETH--RRIVNVDLKFPPFLSDGSKDLISKLLRYH 337

  Fly   863 PADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPP 900
            |..||      ....::.||      |.....::|.||
 Frog   338 PPQRL------PLKGVMEHP------WVKANSRRVLPP 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	75/286 (26%)
aurkb	XP_012809281.1	STKc_Aurora-B_like	96..365	CDD:271019	78/297 (26%)