DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment aPKC and S6KL

DIOPT Version :10

Sequence 1:NP_001260984.1 Gene:aPKC / 47594 FlyBaseID:FBgn0261854 Length:958 Species:Drosophila melanogaster
Sequence 2:NP_524861.2 Gene:S6KL / 45970 FlyBaseID:FBgn0283473 Length:483 Species:Drosophila melanogaster


Alignment Length:286 Identity:91/286 - (31%)
Similarity:146/286 - (51%) Gaps:39/286 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   609 RQYSLND-FELIRVIGRGSYAKVLMVELRR-TRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETA 671
            ::.|.|| :.:..::.:|::..|..|..:. ..:.||:||:||:.:.:|..:..::.|..:.:..
  Fly   151 KETSKNDLYRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVC 215

  Fly   672 SNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGI 736
            .:|||:|.....:|....|..:.|:|..|:|   ..:......:..|.|..||:|||:|||..||
  Fly   216 GHHPFIVKQIDLWQNRHNLHILSEYVPNGEL---FSKITHFSIDLVRLYIGEIALALDFLHNAGI 277

  Fly   737 IYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWAL 801
            ||||.|.:|:||..:.||||||:|:.| .::.|..|.|.|||..|:|||||.||.||.:||||||
  Fly   278 IYRDAKPENILLTEQFHIKLTDFGLSK-WLKLGANTRTMCGTFKYMAPEILCGEPYGHAVDWWAL 341

  Fly   802 GVLLYEMLAGRSP-------------------------FDLAGASENPDQNTEDYLFQVILEKTI 841
            ||:..:||..:||                         ..:.|..::.|.::||:|.:.:     
  Fly   342 GVIACQMLTQKSPNIKRHLLRRRESVEPEDGLSNAPSIAQINGCLQDSDGDSEDFLPEEV----- 401

  Fly   842 RIPRSLSVRAASVLKGFLNKNPADRL 867
               :.|:.....||:..|...|..|:
  Fly   402 ---QHLTHEGRDVLRKLLTIEPRQRI 424

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
aPKCNP_001260984.1 C1_aPKC 496..550 CDD:410344
STKc_aPKC 620..947 CDD:270740 88/274 (32%)
S6KLNP_524861.2 STKc_AGC 167..>354 CDD:270693 75/190 (39%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.