DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aPKC and gwl

DIOPT Version :9

Sequence 1:	NP_001260984.1	Gene:	aPKC / 47594	FlyBaseID:	FBgn0261854	Length:	958	Species:	Drosophila melanogaster
Sequence 2:	NP_524860.2	Gene:	gwl / 45969	FlyBaseID:	FBgn0260399	Length:	846	Species:	Drosophila melanogaster

Alignment Length:	157	Identity:	57/157 - (36%)
Similarity:	97/157 - (61%)	Gaps:	2/157 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   612 SLNDFELIRVIGRGSYAKVLM-VELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHP 675
            ::.||.:|:.|.||::.||.: .:...::|::|:||::|:.:.:...:..|.||::.. ..|...
  Fly    53 TIKDFVIIKPISRGAFGKVFLGYKNNDSKRLFAIKVMRKSEMINKNMVSQVITERNAL-ALSRSQ 116

  Fly   676 FLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRD 740
            |.|.|....|:.|.::.|:|::.||||...:.......|..||||.||:.:||.:||:.||::||
  Fly   117 FCVSLFYSLQSLSYVYLVMEYMVGGDLKSLLAMFGYFDEPTARFYVAEMVMALQYLHQHGIVHRD 181

  Fly   741 LKLDNVLLDHEGHIKLTDYGMCKEGIR 767
            :|.||:||...||:||||:|:.|..:|
  Fly   182 IKPDNMLLSSSGHVKLTDFGLSKIDMR 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556
		S_TKc	616..884	CDD:214567	56/153 (37%)
		STKc_aPKC	620..947	CDD:270740	54/149 (36%)
gwl	NP_524860.2	STKc_MASTL	52..>255	CDD:270761	57/157 (36%)
		S_TKc	57..>205	CDD:214567	54/148 (36%)
		PKc_like	<655..835	CDD:304357
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100