DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aPKC and trc

DIOPT Version :9

Sequence 1:	NP_001260984.1	Gene:	aPKC / 47594	FlyBaseID:	FBgn0261854	Length:	958	Species:	Drosophila melanogaster
Sequence 2:	NP_001262071.1	Gene:	trc / 40165	FlyBaseID:	FBgn0003744	Length:	463	Species:	Drosophila melanogaster

Alignment Length:	386	Identity:	128/386 - (33%)
Similarity:	199/386 - (51%)	Gaps:	73/386 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   613 LNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFL 677
            :.|||.::|||||::.:|.:|:.:.|..:|||||::||.:.:.|.:..|:.|:.|...| :|.::
  Fly    90 VEDFEALKVIGRGAFGEVRLVQKKDTGHVYAMKVLRKADMLEKEQVAHVRAERDVLVEA-DHQWV 153

  Fly   678 VGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLK 742
            |.::..||.|..|:.::||:.|||:|..:.::..|.||..:||.:|.:||::.:|:.|.|:||:|
  Fly   154 VKMYYSFQDPVNLYLIMEFLPGGDMMTLLMKKDTLSEEGTQFYISETALAIDSIHKLGFIHRDIK 218

  Fly   743 LDNVLLDHEGHIKLTDYGMCKEGI---------------RPGDTTSTFC---------------- 776
            .||:|||..||:||:|:|:| .|:               :|.|...| |
  Fly   219 PDNLLLDARGHLKLSDFGLC-TGLKKSHRTDFYRDLSQAKPSDFIGT-CASLSCSPMDSKRRAES 281

  Fly   777 -------------GTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNT 828
                         |||:|||||:.....||.:.|||:|||::||||.|..||    .|:|| |:|
  Fly   282 WKRNRRALAYSTVGTPDYIAPEVFLQTGYGPACDWWSLGVIMYEMLMGYPPF----CSDNP-QDT 341

  Fly   829 EDYLFQVILEKTIRIPRS--LSVRAASVLKGFLNKNPAD-RLGCHRESAFMDIVSHPFFKNMDWE 890
              |...:...:|:..|..  :|..|...:..|..:  || |||..|  ...|:.|.|||:.:|||
  Fly   342 --YRKVMNWRETLIFPPEIPISEEAKETIINFCCE--ADRRLGSQR--GLEDLKSVPFFRGVDWE 400

  Fly   891 LLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQL----TPD-----DDHVIDNIDQSEFE 942
            .:..:....|.:.|  |..|.:|| .||...::::    .|.     .|.|..|.....||
  Fly   401 HIRERPAAIPVEVR--SIDDTSNF-DEFPDVSLEIPSAPIPQGGEIAKDWVFINYTYKRFE 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556
		S_TKc	616..884	CDD:214567	108/314 (34%)
		STKc_aPKC	620..947	CDD:270740	125/379 (33%)
trc	NP_001262071.1	OmpH	16..>85	CDD:214922
trc	NP_001262071.1	STKc_NDR_like	91..455	CDD:270750	126/380 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24356
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010