Protein Alignment aPKC and Stk32c

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_001102392.1
• Gene: Stk32c / 365381
• RGDID: 1305864
• Length: 488
• Species: Rattus norvegicus
• Alignment Length: 371
• Identity: 117/371 - (31%)
• Similarity: 189/371 - (50%)
• Gaps: 38/371 - (10%)

  Fly   551 PEPLVKE-RAEESSDPIPVPLPPLPY----EAMSGGAEACETHDHAHIVAPPPPEDPLEPGTQRQ 610
            |.|...: ||.::.|....|.|...:    :.||..:.:..:       |..|..|..|     .
  Rat    36 PPPAASQPRARDAGDARAQPRPLFQWSKWKKRMSMSSISASS-------ARRPVFDDKE-----D 88

  Fly   611 YSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHP 675
            .:.:.|:::|.||:||:.||.:|:.|.|.::||||.:.|....:.:::..|..|..:.:.. .|.
  Rat    89 VNFDHFQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEI-EHV 152

  Fly   676 FLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRD 740
            |||.|...||....:|.|::.:.||||.||:|:..:..|:..|.|..|::|||::|..:.||:||
  Rat   153 FLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYICEMALALDYLRSQHIIHRD 217

  Fly   741 LKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILR-----GEDYGFSVDWWA 800
            :|.||:|||.:||..|||:.:... |:.|:..:...||..|:||||..     |..|.|.||||:
  Rat   218 VKPDNILLDEQGHAHLTDFNIATI-IKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWS 281

  Fly   801 LGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPAD 865
            :||:.||:|.|..|:|:..:      |..:.|.|:....:::...:.|....::|:..|..||.
  Rat   282 VGVMAYELLRGWRPYDIHSS------NAVESLVQLFSTVSVQYVPTWSKGMVALLRKLLTVNPE- 339

  Fly   866 RLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKP---RLDSD 908
                ||.|:..|:.:.|...::.|:.|..|:|.|.|.|   ||..|
  Rat   340 ----HRFSSLQDMQTAPSLAHVLWDELSEKKVEPGFVPNKGRLHCD 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	103/297 (35%)
Stk32c	NP_001102392.1	STKc_Yank1	93..352	CDD:270730	93/271 (34%)