Protein Alignment aPKC and Pka-C1

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_476977.1
• Gene: Pka-C1 / 34284
• FlyBaseID: FBgn0000273
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 327
• Identity: 117/327 - (35%)
• Similarity: 188/327 - (57%)
• Gaps: 15/327 - (4%)

  Fly   600 EDPLEPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTE 664
            ||..........:|:|||.|:.:|.||:.:|::|:.:.|:..||||::.|..|...:.::....|
  Fly    30 EDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNE 94

  Fly   665 KHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALN 729
            |.:.: |...||||.|...|:..|.|:.|:|:|.||::..|:::..|..|.|:|||||:|.||..
  Fly    95 KRILQ-AIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFE 158

  Fly   730 FLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGF 794
            :||...:||||||.:|:|:|.:|::|:||:|..|   |....|.|.||||.|:||||:..:.|..
  Fly   159 YLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNK 220

  Fly   795 SVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFL 859
            :|||||||||:|||.||..||    .::.|.|     :::.|:...:|.|.........:|:..|
  Fly   221 AVDWWALGVLVYEMAAGYPPF----FADQPIQ-----IYEKIVSGKVRFPSHFGSDLKDLLRNLL 276

  Fly   860 NKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQ 924
            ..:...|.| :.::...||.:..:|.:.||..:.:|::..||.||.....|.:|| .::..||::
  Fly   277 QVDLTKRYG-NLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNF-DDYEEEALR 339

  Fly   925 LT 926
            ::
  Fly   340 IS 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	110/307 (36%)
Pka-C1	NP_476977.1	STKc_PKA	44..333	CDD:271111	112/303 (37%)