Protein Alignment aPKC and Sgk1

DIOPT Version :9

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: XP_006227785.1
• Gene: Sgk1 / 29517
• RGDID: 3668
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 553
• Identity: 183/553 - (33%)
• Similarity: 271/553 - (49%)
• Gaps: 111/553 - (20%)

  Fly   432 TVPMGVAPSSQQMSQHQLQSEEEIEPAYATVFPNVPQAPGLSCDGEDRSIYRRGARRWRKLYRVN 496
            |.|.||         |....|.:.|||...           ||.|:
  Rat    46 TGPAGV---------HLPPGEPDFEPALCQ-----------SCLGD------------------- 71

  Fly   497 GHIFQAKRFNRRAFCAYCQDRIWGLGRQGFKCIQCKLLVHKKCHKLVQKHCTDQPEP-------- 553
             |.||      |...:..:.|.|.:...|        .|.:.|:   ..:...:|:|
  Rat    72 -HTFQ------RGMLSPEESRSWEIQPGG--------EVKEPCN---HANILTKPDPRTFWTSDD 118

  Fly   554 --LVKERAEESSDPIPVPLPPLPYEAMSGGAEAC---ETHDHAHI----------VAPPPPEDP- 602
              .:|:|....:|.|         :.::..:.||   |...:..|          ..|.||..|
  Rat   119 PAFMKQRRMGLNDFI---------QKLANNSYACKHPEVQSYLKISQPQEPELMNANPSPPPSPS 174

  Fly   603 ----LEPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQT 663
                |.|.:......:||..::|||:||:.|||:...:.....||:||::|..:...::...:.:
  Rat   175 QQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMS 239

  Fly   664 EKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLAL 728
            |::|......||||||||..|||..:|:||::::.||:|.||:||:|...|..||||||||:.||
  Rat   240 ERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASAL 304

  Fly   729 NFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYG 793
            .:||...|:|||||.:|:|||.:|||.|||:|:|||.|....|||||||||.|:|||:|..:.|.
  Rat   305 GYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAPEVLHKQPYD 369

  Fly   794 FSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGF 858
            .:||||.||.:|||||.|..||        ..:||.: ::..||.|.:::..:::..|..:|:|.
  Rat   370 RTVDWWCLGAVLYEMLYGLPPF--------YSRNTAE-MYDNILNKPLQLKPNITNSARHLLEGL 425

  Fly   859 LNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGE-- 921
            |.|:...|||.  :..||:|.||.||..::|:.|..|::||||.|.:....||.:|.||||.|
  Rat   426 LQKDRTKRLGA--KDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHFDPEFTEEPV 488

  Fly   922 --AVQLTPDDDHVIDNIDQS--EFEGFEYVNPL 950
              ::..:||...|..::.::  .|.||.|..|:
  Rat   489 PSSIGRSPDSILVTASVKEAAEAFLGFSYAPPM 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556	9/51 (18%)
		S_TKc	616..884	CDD:214567	119/267 (45%)
		STKc_aPKC	620..947	CDD:270740	142/332 (43%)
Sgk1	XP_006227785.1	S_TKc	192..449	CDD:214567	119/267 (45%)
		STKc_SGK	196..518	CDD:270727	142/332 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910