Protein Alignment aPKC and STK32C

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: XP_011537990.1
• Gene: STK32C / 282974
• HGNCID: 21332
• Length: 504
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 119/377 - (31%)
• Similarity: 189/377 - (50%)
• Gaps: 52/377 - (13%)

  Fly   606 GTQRQYSLNDFELIRVIGRGSYAK-----VLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEK 665
            |.:::.:.:.|:::|.||:||:.|     |.:|:.|.|.::||||.:.|....:.:::..|..|.
Human    96 GARKRMNFDHFQILRAIGKGSFGKPCALQVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFREL 160

  Fly   666 HVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNF 730
            .:.:.. .|.|||.|...||....:|.|::.:.||||.||:|:..:..|:..|.|..|::|||::
Human   161 EILQEI-EHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYICEMALALDY 224

  Fly   731 LHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILR-----GE 790
            |..:.||:||:|.||:|||..||..|||:.:... |:.|:..:...||..|:||||..     |.
Human   225 LRGQHIIHRDVKPDNILLDERGHAHLTDFNIATI-IKDGERATALAGTKPYMAPEIFHSFVNGGT 288

  Fly   791 DYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVL 855
            .|.|.||||::||:.||:|.|..|:|:..:      |..:.|.|:....:::...:.|....::|
Human   289 GYSFEVDWWSVGVMAYELLRGWRPYDIHSS------NAVESLVQLFSTVSVQYVPTWSKEMVALL 347

  Fly   856 KGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKP---RLDSDRDLANFPPE 917
            :..|..||.     ||.|:..|:.:.|....:.|:.|..|:|.|.|.|   ||..|       |.
Human   348 RKLLTVNPE-----HRLSSLQDVQAAPALAGVLWDHLSEKRVEPGFVPNKGRLHCD-------PT 400

  Fly   918 FTGEAVQLTPDDDH----------VIDNI-DQSEFEGFEYVNPLLMSLEDCV 958
            |..|.:.|.....|          ..||. |.|:.|. :|       |:||:
Human   401 FELEEMILESRPLHKKKKRLAKNKSRDNSRDSSQSEN-DY-------LQDCL 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	113/350 (32%)
STK32C	XP_011537990.1	STKc_Yank1	105..371	CDD:270730	94/278 (34%)