Protein Alignment aPKC and ppk33

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_588234.1
• Gene: ppk33 / 2539202
• PomBaseID: SPCC162.10
• Length: 338
• Species: Schizosaccharomyces pombe
• Alignment Length: 318
• Identity: 101/318 - (31%)
• Similarity: 168/318 - (52%)
• Gaps: 30/318 - (9%)

  Fly   604 EPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVF 668
            :|......|::.|::..|||:||::.|.:|:.|:|::.:|:|.|.|. ..|:..|..::.|..:.
pombe    18 DPNATNFESVSQFKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKK-KHDEHKIKKLRNEVLLL 81

  Fly   669 ETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHE 733
            ::. |||.|...:|.|:..::::.|.:.:.||||.||:. ||:..|...|.:..|:..||.::|.
pombe    82 QSL-NHPLLCKFYSEFEDETKIYLVTDLMLGGDLRYHIS-QRKFNESVIRIWMVELVSALIYIHS 144

  Fly   734 KGIIYRDLKLDNVLLDHEGHIKLTDYGMCKE---GIRPGDTTSTF--CGTPNYIAPE-ILRGEDY 792
            ||:::||:|.||:|||.:||.||.|:.:..:   ...|..:..|.  .|||.|:||| ::....|
pombe   145 KGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSNMTVGRVGTPVYMAPETLIHAVSY 209

  Fly   793 GFSVDWWALGVLLYEMLAGRSPF------DLAGASENPDQNTEDYLFQVILEKTIRIPR-----S 846
            ..| |||:||:..||.|....||      :...|||....::.|.     |...:.|.|     :
pombe   210 KES-DWWSLGITFYECLFQVRPFPNHLLINWIRASEEEKASSADR-----LSSALHISRDKKLTT 268

  Fly   847 LSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPR 904
            :|..|.|.:..||..:...||| |...   .:.:||||.::..|.:.:..:||.|:|:
pombe   269 ISKDARSAVMAFLEMDIKKRLG-HSSK---KLQTHPFFCSISLETVSKGNLTPIFRPK 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	98/302 (32%)
ppk33	NP_588234.1	Protein Kinases, catalytic domain	29..302	CDD:473864	92/285 (32%)