Protein Alignment aPKC and Prkacb

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_001157672.1
• Gene: Prkacb / 18749
• MGIID: 97594
• Length: 398
• Species: Mus musculus
• Alignment Length: 330
• Identity: 120/330 - (36%)
• Similarity: 187/330 - (56%)
• Gaps: 24/330 - (7%)

  Fly   597 PPPEDPLEPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWV 661
            |||.:.         .|.|||..:.:|.||:.:|::|:.:.|.:.||||::.|..|...:.|:..
Mouse    81 PPPSNA---------GLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHT 136

  Fly   662 QTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISL 726
            ..||.:.: |...||||.|...|:..|.|:.|:|:|.||::..|::|..|..|.|||||||:|.|
Mouse   137 LNEKRILQ-AVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVL 200

  Fly   727 ALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGED 791
            ...:||...:||||||.:|:|:||:|:|::||:|..|   |....|.|.||||.|:||||:..:.
Mouse   201 TFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKG 262

  Fly   792 YGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLK 856
            |..:|||||||||:|||.||..||    .::.|.|     :::.|:...:|.|...|.....:|:
Mouse   263 YNKAVDWWALGVLIYEMAAGYPPF----FADQPIQ-----IYEKIVSGKVRFPSHFSSDLKDLLR 318

  Fly   857 GFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGE 921
            ..|..:...|.| :.::...||.:|.:|...||..:.:::|..||.|:.....|.:|| .::..|
Mouse   319 NLLQVDLTKRFG-NLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNF-DDYEEE 381

  Fly   922 AVQLT 926
            .::::
Mouse   382 EIRVS 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	113/307 (37%)
Prkacb	NP_001157672.1	STKc_PKA	89..378	CDD:271111	115/303 (38%)