Protein Alignment aPKC and sgk-1

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_001041299.1
• Gene: sgk-1 / 181697
• WormBaseID: WBGene00004789
• Length: 463
• Species: Caenorhabditis elegans
• Alignment Length: 370
• Identity: 142/370 - (38%)
• Similarity: 218/370 - (58%)
• Gaps: 34/370 - (9%)

  Fly   592 HIVAPPPPED--PLEPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTD 654
            |:.:|...|:  .|.|..::..:.|||:.:..||:||:.:|..|..:.|::|||||::.|..:..
 Worm   109 HLESPDDDENNVDLGPSERKTATANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRK 173

  Fly   655 DEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARF 719
            ..::..|..|::|......|||||.||..||...:|:||::.:.||:|..|:||::...|..:||
 Worm   174 KNEVKHVMAERNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRF 238

  Fly   720 YAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAP 784
            |||||:.||.:||||.|||||||.:|:|||.:|::.|||:|:|||.::...|||||||||.|:||
 Worm   239 YAAEIACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAP 303

  Fly   785 EILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSV 849
            ||:..:.|..:||||.||.:||||:.|..||      .:.|.|.   ::..|:.:.:|:..::||
 Worm   304 EIILKKPYDKTVDWWCLGSVLYEMIFGLPPF------YSKDHNE---MYDKIINQPLRLKHNISV 359

  Fly   850 RAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANF 914
            ..:.::.|.|.|:.:.||| ||.. |.||..||||..:||:.|..:::..||.|::.:..|.:|.
 Worm   360 PCSELITGLLQKDRSKRLG-HRND-FRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSNI 422

  Fly   915 PPEFTGEAVQLTPDD-----------DHVIDNIDQSEFEGFEYVN 948
            ..||.  .:|:.|..           ||        :||.|.:|:
 Worm   423 SKEFV--EIQIDPSSLAPQQLAVTHRDH--------DFENFTFVD 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	133/337 (39%)
sgk-1	NP_001041299.1	STKc_SGK	139..456	CDD:270727	133/337 (39%)