Protein Alignment aPKC and sax-1

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_508627.5
• Gene: sax-1 / 180655
• WormBaseID: WBGene00004727
• Length: 476
• Species: Caenorhabditis elegans
• Alignment Length: 357
• Identity: 120/357 - (33%)
• Similarity: 188/357 - (52%)
• Gaps: 61/357 - (17%)

  Fly   612 SLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPF 676
            ::||||.::|||||::.:|.:|:...|..|||||:::|:.:.:.|....|:.|:.:...| :..:
 Worm    83 TVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEA-DCDW 146

  Fly   677 LVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDL 741
            :|.::..||..|.|:.|:||:.|||:|..:.::..|.||..:||.||.:||:.|:|..|.|:||:
 Worm   147 VVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQFYIAEAALAIQFIHSLGFIHRDI 211

  Fly   742 KLDNVLLDHEGHIKLTDYGMCKEGIR---------------PGDTTS------------------ 773
            |.||:|||..||:||:|:|:| .|::               |.|..|
 Worm   212 KPDNLLLDARGHVKLSDFGLC-TGLKKFHRTDHYRNWPSTLPPDFISKPFESKRKAETWKRNRRA 275

  Fly   774 ---TFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQV 835
               :..|||:|||||:.:...|..|.|||:|||::||||.|..||    .||.|.   |.|...:
 Worm   276 YAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGVIMYEMLIGYPPF----CSELPQ---ETYRKVI 333

  Fly   836 ILEKTIRIPRS--LSVRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVT 898
            ..::|:..|..  :|:.|.:.:|.|..: ...|||.|  ....:|...||.|.:||..:..:  .
 Worm   334 NWQQTLVFPSDVPISIEAKATIKRFCCE-AERRLGNH--GGLDEIKQCPFVKRIDWNHIRER--P 393

  Fly   899 PPFKPRLDSDRDLANFPPEFTGEAVQLTPDDD 930
            ||.:..:.|..|.:|| .:|        ||:|
 Worm   394 PPIRVTVKSIDDTSNF-DDF--------PDED 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	116/349 (33%)
sax-1	NP_508627.5	MobB_NDR-like	18..82	CDD:439270
		STKc_NDR_like	85..443	CDD:270750	120/355 (34%)