Protein Alignment aPKC and F31E3.2

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_498522.3
• Gene: F31E3.2 / 175977
• WormBaseID: WBGene00017950
• Length: 441
• Species: Caenorhabditis elegans
• Alignment Length: 393
• Identity: 118/393 - (30%)
• Similarity: 189/393 - (48%)
• Gaps: 69/393 - (17%)

  Fly   532 KLLVHKKCHKLVQKHCTDQPEPLVKERA--EESSDPIPVPLPPLPYEAMSGGAEACETHDHAHIV 594
            ||....:..||  |.|    .|.:|.|.  .|.:|    |.||:|...:.         |:....
 Worm    48 KLAFKSRLQKL--KKC----RPHLKRRTYKVEEAD----PRPPVPRFIVD---------DYGDYE 93

  Fly   595 APPP---------------PEDPLEPGTQRQYSLNDFELIRVIGRGSYAKVLMVE-LRRTRRIYA 643
            .|.|               ||.|    |:...:...|.|.|.:||||:..|.... :..:.|.:|
 Worm    94 KPEPTRKEFAIPWFEHLFLPEFP----TRSVINEKSFVLERQLGRGSFGVVYCASAIHDSERKFA 154

  Fly   644 MKVIKKALVTDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRG--GDLMYHM 706
            :|:.:|..:.....:..|:.|..:.....:|||:...:|.:||.:.|:.::::..|  ||| :.:
 Worm   155 IKMQEKREIISKRAVLQVKREASIQRLLPSHPFIARTYSTWQTRTHLYSLLQYPTGSTGDL-FSV 218

  Fly   707 QRQR-RLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGD 770
            .||| .|.|...|...||::.|::|||:..:||||:||:||:||..||..|.|:|:.|: ::.|.
 Worm   219 WRQRGSLSEAAIRLIGAELASAIDFLHQNDVIYRDVKLENVVLDQWGHALLIDFGLAKK-LKQGS 282

  Fly   771 TTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQV 835
            :|.|.|||..|::|::..|..|...||||:|||||:.:|.|..|:..:.|:.:.:....||
 Worm   283 STGTICGTLQYMSPDVASGGTYSHYVDWWSLGVLLHILLTGIYPYPNSEATHHANLKFIDY---- 343

  Fly   836 ILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGC----HRESAFMDIVSHPFFKNMDWELLERKQ 896
                  ..|...|...|:::         ||:..    ||..:|..:.:||||:::|:..||:|.
 Worm   344 ------STPIGCSREFANLM---------DRMLAVSITHRLCSFTVLHAHPFFRSIDFSKLEQKD 393

  Fly   897 VTP 899
            .||
 Worm   394 YTP 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344	6/17 (35%)
		STKc_aPKC	620..947	CDD:270740	94/288 (33%)
F31E3.2	NP_498522.3	STKc_AGC	132..381	CDD:270693	85/269 (32%)