Protein Alignment aPKC and Akt2

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_031460.1
• Gene: Akt2 / 11652
• MGIID: 104874
• Length: 481
• Species: Mus musculus
• Alignment Length: 341
• Identity: 145/341 - (42%)
• Similarity: 223/341 - (65%)
• Gaps: 19/341 - (5%)

  Fly   612 SLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPF 676
            ::|||:.::::|:|::.||::|..:.|.|.||||:::|.::...:::....||..|.:. :.|||
Mouse   148 TMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQN-TRHPF 211

  Fly   677 LVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDL 741
            |..|...|||..||.||:|:..||:|.:|:.|:|...|:.||||.|||..||.:||.:.::|||:
Mouse   212 LTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHSRDVVYRDI 276

  Fly   742 KLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLY 806
            ||:|::||.:||||:||:|:|||||..|.|..||||||.|:|||:|...|||.:||||.|||::|
Mouse   277 KLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMY 341

  Fly   807 EMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGCHR 871
            ||:.||.||      .|.|   .:.||::||.:.||.||:|...|.|:|.|.|.|:|..|||...
Mouse   342 EMMCGRLPF------YNQD---HERLFELILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGP 397

  Fly   872 ESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQLTPDDDHVIDNI 936
            ..| .:::.|.||.:::|:.:.:|::.|||||::.|:.|...|..|||.:::.:||.|.:  |::
Mouse   398 SDA-KEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRY--DSL 459

  Fly   937 D------QSEFEGFEY 946
            |      ::.|..|.|
Mouse   460 DPLELDQRTHFPQFSY 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	142/333 (43%)
Akt2	NP_031460.1	PH_PKB	4..111	CDD:269947
		STKc_PKB_beta	156..478	CDD:173686	142/333 (43%)