Protein Alignment aPKC and Aurkb

DIOPT Version :10

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_446201.1
• Gene: Aurkb / 114592
• RGDID: 621625
• Length: 343
• Species: Rattus norvegicus
• Alignment Length: 304
• Identity: 82/304 - (26%)
• Similarity: 156/304 - (51%)
• Gaps: 35/304 - (11%)

  Fly   603 LEPGTQRQ-YSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDW-----V 661
            |:....|| :::::||:.|.:|:|.:..|.:...:::|.|.|:|::.|:.: :.|.::.     :
  Rat    66 LQGSQSRQPFTIDNFEIGRPLGKGKFGNVYLAREKKSRFIVALKILFKSQI-EKEGVEHQLRREI 129

  Fly   662 QTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISL 726
            :.:.|:     .||.::.|::.|....|::.::|:...|:|...:|:.....|:.......|:|.
  Rat   130 EIQAHL-----KHPNILQLYNYFYDQQRIYLILEYAPRGELYKELQKSGTFDEQRTATIMEELSD 189

  Fly   727 ALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGED 791
            ||.:.|:|.:|:||:|.:|:||..:|.:|:.|:|.....  |.....|.|||.:|:.||::.|..
  Rat   190 ALMYCHKKKVIHRDIKPENLLLGLQGELKIADFGWSVHA--PSLRRKTMCGTLDYLPPEMIEGRM 252

  Fly   792 YGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLK 856
            :...||.|.:|||.||::.|..||:....||.         ::.|::..::.|.|:.:.|..::.
  Rat   253 HNEMVDLWCIGVLCYELMVGNPPFESPSHSET---------YRRIVKVDLKFPSSMPLGAKDLIS 308

  Fly   857 GFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPP 900
            ..|..||:.||...:.||      ||      |.....::|.||
  Rat   309 KLLKHNPSQRLPLEQVSA------HP------WVRANSRRVLPP 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_aPKC	496..550	CDD:410344
		STKc_aPKC	620..947	CDD:270740	77/286 (27%)
Aurkb	NP_446201.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..57
		STKc_Aurora-B_like	75..342	CDD:271019	79/295 (27%)