Protein Alignment aPKC and akt1

DIOPT Version :9

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: NP_001268730.1
• Gene: akt1 / 101910198
• ZFINID: ZDB-GENE-130730-1
• Length: 474
• Species: Danio rerio
• Alignment Length: 427
• Identity: 165/427 - (38%)
• Similarity: 247/427 - (57%)
• Gaps: 42/427 - (9%)

  Fly   527 KCIQCKLLVHKKCHKLVQKHCTDQPEPLVKERAE--ESSDPIPVPLPPLPYEAMSGGAEACETHD 589
            :|:|...::.:..|       .:.||    ||.|  ::...:...|.....|.|...||    |.
Zfish    77 RCLQWTTVIERTFH-------VETPE----ERQEWTKAIQTVAESLQKQEEEMMDASAE----HT 126

  Fly   590 HAHIVAPPPPEDPLEPGTQRQYSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTD 654
            ........||         .:.:::|||.::::|:|::.||::|:.:.|.:.||||::||.::..
Zfish   127 DMETSLSKPP---------HKVTMHDFEYLKLLGKGTFGKVILVKEKATGKYYAMKILKKEVIVA 182

  Fly   655 DEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARF 719
            .:::....||..|.:. |.||||..|.|.|||...|.||:|:..||:|.:|:.|:|...||.|.|
Zfish   183 KDEVAHTLTENRVLQN-SRHPFLTALKSSFQTHDHLCFVMEYANGGELFFHLSRERVFSEERACF 246

  Fly   720 YAAEISLALNFLH-EKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIA 783
            |.|||..||::|| |:.::||||||:|::||.:||:|:||:|:|||||..|.|..||||||.|:|
Zfish   247 YGAEIVSALHYLHSERNVVYRDLKLENLMLDKDGHVKITDFGLCKEGITDGATMKTFCGTPEYLA 311

  Fly   784 PEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLS 848
            ||:|...|||.:||||.|||::|||:.||.||      .|.|   .:.||::||.:.||.||:|:
Zfish   312 PEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF------YNQD---HERLFELILMEDIRFPRTLA 367

  Fly   849 VRAASVLKGFLNKNPADRLGCHRESAFMDIVSHPFFKNMDWELLERKQVTPPFKPRLDSDRDLAN 913
            ..|.|:|.|.|.|:|..|||...:.| .:|:.|.||..:.|:.:..|::.|||||::.|:.|...
Zfish   368 PDAKSLLSGLLKKDPMQRLGGGPDDA-KEIMQHKFFTGIVWQDVYEKKLVPPFKPQVTSETDTRY 431

  Fly   914 FPPEFTGEAVQLTP--DDD--HVIDNIDQSEFEGFEY 946
            |..||||:.:.:||  .||  ...|:..:..|..|.|
Zfish   432 FDEEFTGQTITITPPGQDDCMEAFDSERRPHFPQFSY 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556	3/22 (14%)
		S_TKc	616..884	CDD:214567	124/268 (46%)
		STKc_aPKC	620..947	CDD:270740	146/332 (44%)
akt1	NP_001268730.1	PH_PKB	5..112	CDD:269947	8/45 (18%)
		PKc_like	120..473	CDD:328722	154/373 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910