DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment aPKC and LOC101732362

DIOPT Version :9

Sequence 1:	NP_001260984.1	Gene:	aPKC / 47594	FlyBaseID:	FBgn0261854	Length:	958	Species:	Drosophila melanogaster
Sequence 2:	XP_004918050.3	Gene:	LOC101732362 / 101732362	-ID:	-	Length:	292	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	112/286 - (39%)
Similarity:	164/286 - (57%)	Gaps:	18/286 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   664 EKHVFE--TASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISL 726
            ||.:.:  |::.|||||.|::.||:.:.||||::::.||||.:.::.|....|..|.||.|.|.|
Frog    19 EKRILQKVTSAEHPFLVSLYATFQSENHLFFVMKYLPGGDLCHLLEHQGAFEESKAMFYTACIVL 83

  Fly   727 ALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGED 791
            .|..||...|::|||||:|:::|..|::|:.|:|:.|:|.|.||.:.|.|||..|:||||:....
Frog    84 GLEELHRNNIVHRDLKLENLMVDVHGYLKIVDFGLSKDGFRYGDRSKTRCGTNCYMAPEIIDEMA 148

  Fly   792 YGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLK 856
            |..:||||||||:||.|:..:.|||.....|         ||:.|......:...||..|..::.
Frog   149 YSRAVDWWALGVVLYVMIMFQFPFDAEDDME---------LFESIRNDKPALTEELSEEAQCLIL 204

  Fly   857 GFLNKNPADRLGCHRESAFMDIVSHPFFKNMDW-ELLERKQVTPPFKPRLDSDRDLANFPPEFTG 920
            ..|.|||..||| ..|:...::.:|.||:::|| |.|||:|: |||||.:..   |.....:...
Frog   205 RLLEKNPCHRLG-SSEAGAEEVKAHEFFEDIDWEEFLEREQM-PPFKPDVSG---LTESTRQSEC 264

  Fly   921 EAVQLTPDDDHVIDNIDQSEFEGFEY 946
            :|..|.|..: .|....|..||||:|
Frog   265 QAWGLMPPAE-AISPEAQELFEGFDY 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556
		S_TKc	616..884	CDD:214567	87/221 (39%)
		STKc_aPKC	620..947	CDD:270740	112/286 (39%)
LOC101732362	XP_004918050.3	PKc_like	15..292	CDD:419665	112/286 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910