Protein Alignment aPKC and prkceb

DIOPT Version :9

• Sequence 1: NP_001260984.1
• Gene: aPKC / 47594
• FlyBaseID: FBgn0261854
• Length: 958
• Species: Drosophila melanogaster
• Sequence 2: XP_002664164.2
• Gene: prkceb / 100332055
• ZFINID: ZDB-GENE-081028-47
• Length: 738
• Species: Danio rerio
• Alignment Length: 601
• Identity: 232/601 - (38%)
• Similarity: 316/601 - (52%)
• Gaps: 138/601 - (22%)

  Fly   474 CDGEDRSI-------YRRGARRWRKLYRVNGHIFQAKRFNRRAFCAYCQDRIWG-LGRQGFKCIQ 530
            |:.|:|..       .|:||.| |::::||||.|.|....:..:|::|:|.||| ||:||::|..
Zfish   141 CENEERVFRERMRPRKRQGAVR-RRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVLGKQGYQCQV 204

  Fly   531 CKLLVHKKCHKLVQKHCT------DQPEPL----------------------------------- 554
            |..:|||:||:|:...|.      |..|.:
Zfish   205 CTCVVHKRCHELIITKCAGLKKQEDTAEEVGSQRFSVNMPHKFRIHNYKVLTFCDHCGSLLWGLL 269

  Fly   555 ------------VKERAE---------------------------------------ESSDPIPV 568
                        |.:|.|                                       :..||.|:
Zfish   270 RQGLQCKVCKMNVHKRCEINVAPNCGVDARGIAKVLSDLGVTPDKLSGSVQRRKKISQGPDPHPL 334

  Fly   569 PLPPLPYE--AMSGGAEACE-------------THDHAHIVAPPPPED-PLEPGTQRQ------- 610
            |:.||..|  ..|.....|:             :.||.........|. ..|.|..|:
Zfish   335 PISPLLEEDRCKSAPTSPCDQDIKDLENIRKALSFDHRSEEMKQASEGVSEETGEARENGEVKTV 399

  Fly   611 ----YSLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETA 671
                ..|.||..|:|:|:||:.||::.|||.|..::|:||:||.::..|:|:|...|||.:...|
Zfish   400 QAKRMMLEDFSFIKVLGKGSFGKVMLAELRGTDEVFAVKVLKKDVILQDDDVDCTMTEKRILALA 464

  Fly   672 SNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGI 736
            ..||:|..|:.||||..|||||:|:|.|||||:.:||.|:..|..:||||||::.||.|||..|:
Zfish   465 RKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEARSRFYAAEVTSALMFLHHNGV 529

  Fly   737 IYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWAL 801
            |||||||||:|||.|||.||.|:|||||||..|.||:||||||:|||||||:..:||.|||||||
Zfish   530 IYRDLKLDNILLDAEGHCKLADFGMCKEGILDGITTTTFCGTPDYIAPEILQELEYGPSVDWWAL 594

  Fly   802 GVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADR 866
            |||:|||:||:.||         :.:.||.||:.||...:..|..||..|.|:||.|:.|:|:.|
Zfish   595 GVLMYEMMAGQPPF---------EADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKSPSKR 650

  Fly   867 LGCHRESAFMDIVS-HPFFKNMDWELLERKQVTPPFKPRLDSDRDLANFPPEFTGEAVQLTPDDD 930
            |||.......|.:. |||||::||.|||:::|.||||||:.:.||:.||..:||.|...|||.:|
Zfish   651 LGCVVSQGLEDAIKVHPFFKDIDWVLLEQRKVKPPFKPRIKTKRDVNNFDQDFTREEPVLTPVED 715

  Fly   931 HVIDNIDQSEFEGFEY 946
            .:|..|:|.||:||.|
Zfish   716 AIIKQINQEEFKGFSY 731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aPKC	NP_001260984.1	C1_1	498..550	CDD:278556	22/58 (38%)
		S_TKc	616..884	CDD:214567	143/268 (53%)
		STKc_aPKC	620..947	CDD:270740	175/328 (53%)
prkceb	XP_002664164.2	C2_PKC_epsilon	3..135	CDD:175981
		C1_1	171..221	CDD:278556	21/49 (43%)
		C1_1	245..297	CDD:278556	3/51 (6%)
		STKc_nPKC_epsilon	413..733	CDD:270743	175/328 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D222529at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920